Objective: To examine the association between sleep disturbances and cardiovascular health in Brazilian adults. Methods: We analyzed cross-sectional data from a nationally representative sample of 36,480 Brazilian adults ages 18 and over. Multivariate Poisson regression models were used to assess the association between sleep disturbances (difficulty falling asleep, frequent interruptions in sleep, or sleeping more than usual) and Life's Simple 7 (LS7) cardiovascular health (CVH) scores through consideration of four behaviors (smoking, physical activity, body mass index, and diet) and three biological factors (hypercholesterolemia, hypertension, and diabetes). Results: Adults with no sleep disturbances had better CVH, with higher mean LS7 CVH scores (4.2, 95% confi-dence interval [CI]: 4.1; 4.2) when compared to those experiencing some level of sleep disturbance within a 2-week timespan (3.8, 95% CI: 3.7; 3.8). Specifically, compared to those with no sleep disturbance, adults reporting sleep disturbances for half of the weekdays had significantly lower LS7 CVH mean scores (beta =-0.02, 95% CI:-0.04; 0.01). Adults who had disturbances more than half of the weekdays had even lower scores (beta =-0.06, 95% CI:-0.09;-0.02), followed by those who reported disturbances almost every day (beta =-0.08, 95% CI:-0.11;-0.04), even after adjusting for age, sex, education status, depressive symptoms, and night shift work. Conclusion: Brazilian adults with sleep disturbances are less likely to achieve ideal CVH. Given that sleep disturbances seem to be increasingly common in Brazil, recent gains in CVH mortality may be affected. (C) 2020 National Sleep Foundation. Published by Elsevier Inc. All rights reserved.