Can genetics reveal the causes and consequences of educational attainment?

被引：1

作者：

Munafo, Marcus ^{[1
]}

Davies, Neil M. ^{[1
]}

Smith, George Davey ^{[1
]}

机构：

[1] Univ Bristol, Bristol, Avon, England

来源：

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY | 2020年 / 183卷 / 02期

基金：

英国经济与社会研究理事会; 英国医学研究理事会;

关键词：

Causal inference; Education; Genetic structure; Mendelian randomization; MENDELIAN RANDOMIZATION; ALCOHOL EXPOSURE; WIDE ASSOCIATION; ADULT MORTALITY; HEALTH; METAANALYSIS; CHILDREN; SCHOOL; SKILLS;

D O I：

10.1111/rssa.12543

中图分类号：

O1 [数学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 0701 ; 070101 ;

摘要：

There is an extensive literature on the causes of educational inequalities, and the life course consequences of educational attainment. Mendelian randomization, where genetic variants associated with exposures of interest are used as proxies for those exposures, often within an instrumental variables framework, has proven highly effective at elucidating the causal effects of several risk factors in the biomedical sciences. We discuss the potential for this approach to be used in the context of social and socio-economic exposures and outcomes, such as educational attainment.

引用

页码：681 / 688

页数：8

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