Tailored Vessel-Catheter Diameter Ratio in a Direct Aspiration First-Pass Technique: Is It a Matter of Caliber?

BACKGROUND AND PURPOSE: The aspiration technique has gained a prominent role in mechanical thrombectomy. The thrombectomy goal is successful revascularization (modified TICI???2b) and first-pass effect. The purpose of this study was to evaluate the impact of the vessel-catheter ratio on the modified TICI???2b and first-pass effect. MATERIALS AND METHODS: This was a retrospective, single-center, cohort study. From January 2018 to April 2020, 111/206 (53.9%) were eligible after applying the exclusion criteria. Culprit vessel diameters were measured by 2 neuroradiologists, and the intraclass correlation coefficient was calculated. The receiver operating characteristic curve was used for assessing the vessel-catheter ratio cutoff for modified TICI???2b and the first-pass effect. Time to groin puncture and fibrinolysis were weighted using logistic regression. All possible intervals (interval size, 0.1; sliding interval, 0.01) of the vessel-catheter ratio were plotted, and the best and worst intervals were compared using the ?(2) test. RESULTS: Modified TICI???2b outcome was achieved in 75/111 (67.5%), and first-pass effect was achieved in 53/75 (70.6%). The MCA diameter was 2.1?mm with an intraclass correlation coefficient of 0.92. The optimal vessel-catheter ratio cutoffs for modified TICI???2b were ?1.51 (accuracy = 0.67; 95% CI, 0.58?0.76; P =?0.001), and for first-pass effect, they were significant (?1.33; P = .31). The modified TICI???2b odds ratio and relative risk were 9.2 (95% CI, 2.4?36.2; P = 0.002) and 3.2 (95% CI, 1.2?8.7; P = .024). The odds ratio remained significant after logistic regression (7.4; 95% CI, 1.7?32.5; P = .008). First-pass effect odds ratio and relative risk were not significant (2.1 and 1.5; P?>?.05, respectively). The modified TICI???2b best and worst vessel-catheter ratio intervals were not significantly different (55.6% versus 85.7%, P = .12). The first-pass effect best vessel-catheter ratio interval was significantly higher compared with the worst one (78.6% versus 40.0%, P = .03). CONCLUSIONS: The aspiration catheter should be selected according to culprit vessel diameter. The optimal vessel-catheter ratio cutoffs were ?1.51 for modified TICI???2b with an odds ratio of 9.2 and a relative risk of 3.2.