Evaluation of the Effect of Four Fibers on Laxation, Gastrointestinal Tolerance and Serum Markers in Healthy Humans

被引:54
作者
Stewart, Maria L. [1 ]
Nikhanj, Soma D. [1 ]
Timm, Derek A. [1 ]
Thomas, William [2 ]
Slavin, Joanne L. [1 ]
机构
[1] Univ Minnesota, Dept Food Sci & Nutr, St Paul, MN USA
[2] Univ Minnesota, Sch Publ Hlth, Div Biostat, Minneapolis, MN 55455 USA
基金
美国国家卫生研究院;
关键词
Pullulan; Resistant starch; Short-chain fatty acids; Gas production; Cholesterol; Ghrelin; IN-VITRO FERMENTATION; CHAIN FATTY-ACIDS; RESISTANT STARCH; METABOLIC VARIABLES; HIGH-AMYLOSE; AMYLOPECTIN STARCH; FECAL BULK; GLUCOSE; NUTRIOSE(R)FB; CONSUMPTION;
D O I
10.1159/000275962
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Average dietary fiber intake in the United States is roughly half of the recommended amount. As new dietary fiber products are introduced to increase fiber intake, it is critical to evaluate the physiological effects of such fibers. Aims: This study examined the effect of 4 fibers derived from maize or tapioca on fecal chemistry, gastrointestinal (GI) symptoms and serum markers of chronic disease. Methods: Twenty healthy subjects completed the single-blind crossover study in which 12 g/day of fiber (pullulan, Promitor (TM) Resistant Starch, soluble fiber dextrin or Promitor Soluble Corn Fiber) or placebo (maltodextrin) were consumed for 14 days followed by a 21-day washout. GI symptom surveys were completed (days 3 and 14), stools were collected (days 11-14), diet was recorded (days 12-14) and fasting blood samples were obtained (day 15). Results: The 4 test fibers were well tolerated, with mild to moderate GI symptoms. Total short-chain fatty acid (SCFA) concentrations did not differ among the treatments. Fecal pH and individual SCFAs were affected by some treatments. Stool weight and serum markers of chronic disease did not change with these treatments. Conclusion: Increasing fiber intake by 12 g/day was well tolerated and may have a positive impact on colon health due to fermentation. Copyright (C) 2010 S. Karger AG, Basel
引用
收藏
页码:91 / 98
页数:8
相关论文
共 36 条
[1]  
[Anonymous], 2002, Circulation, V106
[2]  
[Anonymous], 2005, DIETARY REFERENCE IN, DOI DOI 10.17226/10490
[3]   DIETS CONTAINING HIGH AMYLOSE VS AMYLOPECTIN STARCH - EFFECTS ON METABOLIC VARIABLES IN HUMAN-SUBJECTS [J].
BEHALL, KM ;
SCHOLFIELD, DJ ;
YUHANIAK, I ;
CANARY, J .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1989, 49 (02) :337-344
[4]   EFFECT OF LONG-TERM CONSUMPTION OF AMYLOSE VS AMYLOPECTIN STARCH ON METABOLIC VARIABLES IN HUMAN-SUBJECTS [J].
BEHALL, KM ;
HOWE, JC .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1995, 61 (02) :334-340
[5]   Konjac acts as a natural laxative by increasing stool bulk and improving colonic ecology in healthy adults [J].
Chen, Hsiao-Ling ;
Cheng, Han-Chung ;
Liu, Yann-Jiu ;
Liu, Su-Yuan ;
Wu, Wen-Tze .
NUTRITION, 2006, 22 (11-12) :1112-1119
[6]   In vitro fermentation of high-amylose cornstarch by a mixed population of colonic bacteria [J].
Christl, SU ;
Katzenmaier, U ;
Hylla, S ;
Kasper, H ;
Scheppach, W .
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 1997, 21 (05) :290-295
[7]   Digestion and physiological properties of resistant starch in the human large bowel [J].
Cummings, JH ;
Beatty, ER ;
Kingman, SM ;
Bingham, SA ;
Englyst, HN .
BRITISH JOURNAL OF NUTRITION, 1996, 75 (05) :733-747
[8]   A review of the clinical toleration studies of polydextrose in food [J].
Flood, MT ;
Auerbach, MH ;
Craig, SAS .
FOOD AND CHEMICAL TOXICOLOGY, 2004, 42 (09) :1531-1542
[9]   Arabinoxylan consumption decreases postprandial serum glucose, serum insulin and plasma total ghrelin response in subjects with impaired glucose tolerance [J].
Garcia, A. L. ;
Otto, B. ;
Reich, S-C ;
Weickert, M. O. ;
Steiniger, J. ;
Machowetz, A. ;
Rudovich, N. N. ;
Moehlig, M. ;
Katz, N. ;
Speth, M. ;
Meuser, F. ;
Doerfer, J. ;
Zunft, H-J F. ;
Pfeiffer, A. H. F. ;
Koebnick, C. .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2007, 61 (03) :334-341
[10]   A solubilized cellulose fiber decreases peak postprandial cholecystokinin concentrations after a liquid mixed meal in hypercholesterolemic men and women [J].
Geleva, D ;
Thomas, W ;
Gannon, MC ;
Keenan, JM .
JOURNAL OF NUTRITION, 2003, 133 (07) :2194-2203