Antioxidant and antimicrobial activity evaluation and essential oil analysis of Semenovia tragioides Boiss. from Iran

This study reports the essential oil composition, antioxidant and antimicrobial activity of the essential oil and methanol extract of aerial parts of Semenovia tragioides. GC and GC/MS analysis identified 17 compounds representing 99.4% of the oil. The main components comprising 61.9% of the oil were lavandulyl acetate (25.5%), geranyl acetate (12.5%), trans-beta-ocimene (8.8%), p-cymene (7.7%) and gamma-terpinene (7.4%). The samples were screened for their antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and beta-carotene/linoleic acid assay methods. None of the plant samples showed appreciable antioxidant activity in DPPH test. However, methanol extract exhibited considerable linoleic acid oxidation inhibition (77.4%) in the beta-carotene/linoleic acid test, a value near to that of butylated hydroxytoluene (BHT, 95.6%). Total phenolic content of the plant extract as gallic acid equivalents was 7.5 mu g/mg. The essential oil exhibited strong antimicrobial activity against all but one of the tested microorganisms while the plant extract only inhibited two of them weakly. (C) 2010 Elsevier Ltd. All rights reserved.