Protective effect of symmetrical N-heterocyclic 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives against Pepino mosaic virus of tomato

被引:0
作者
Imane, Kasmi [1 ]
Siham, Esserti [1 ]
Kacem, Makroum [1 ]
Malika, Belfaizea [1 ]
Tayeb, Koussa [1 ]
Aicha, Rifai Lalla [1 ]
Lydia, Faize [2 ]
Stephane, Venisse Jean [3 ]
Fouad, Bentiss [4 ]
Amal, Smaili [1 ]
Mohamed, Faize [1 ]
机构
[1] Univ Chouaib Doukkali, Fac Sci, URL CNRST, Lab Plant Biotechnol Ecol & Ecosyst Valorizat, El Jadida, Morocco
[2] CEBAS CSIC, Dept Plant Breeding, Grp Fruit Tree Biotechnol, Murcia, Spain
[3] Univ Clermont Auvergne, PIAF, INRAE, Clermont Ferrand, France
[4] Univ Chouaib Doukkali, Fac Sci, Lab Catalysis & Corros Mat, El Jadida, Morocco
关键词
1; 3; 4-oxadiazole; 4-Thiadiazole; antioxidants enzymes; dihydrotetrazine; PepMV; tomato; ANTIOXIDANT ENZYMES; ANTIVIRAL ACTIVITY; SALICYLIC-ACID; RESISTANCE; GROWTH; FUNGAL;
D O I
10.1111/jph.13105
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Pepino mosaic virus (PepMV) is a highly infectious potexvirus, which has presently become a major pathogen for tomato crops worldwide. Since there is no effective method control for PepMV, strict preventive hygienic measures and cross-protection have been established. However, the use of mild isolates to protect against aggressive isolates provides opportunities for interaction with other microorganisms, which under certain conditions may worsen disease symptoms. Thus, alternative control methods are needed. In this study we aimed at the development of chemical control against PepMV based on the use of heterocyclic compounds including symmetrical 2,5-disubstituted 1,3,4-oxadiazoles, symmetrical 2,5-disubstituted 1,3,4-thiadiazole and dihydrotetrazine derivatives. Results showed that spray application of three 1,3,4-oxadiazole derivatives (OH-Oxa, CH3-Oxa, NO2-Oxa) and of the derivative of 1,3,4-thiadiazole (OH-Thia) resulted in reducing the main symptoms of PepMV in tomato leaves, conversely to the dihydrotetrazine carboxylic acid. Double-antibody sandwich enzyme-linked immunosorbent assay (DAS-ELISA) revealed that PepMV was not detected from tomato plants pre-treated with the derivatives conferring elevated protection. Moreover, the protective ability of OH-Oxa, CH3-Oxa, NO2-Oxa and OH-Thia was closely related to the enhancement of the activity of antioxidant enzymes upon infection with PepMV.
引用
收藏
页码:557 / 573
页数:17
相关论文
共 62 条
[21]   Emerging Viral Diseases of Tomato Crops [J].
Hanssen, Inge M. ;
Lapidot, Moshe ;
Thomma, Bart P. H. J. .
MOLECULAR PLANT-MICROBE INTERACTIONS, 2010, 23 (05) :539-548
[22]   Pepino mosaic virus: a successful pathogen that rapidly evolved from emerging to endemic in tomato crops [J].
Hanssen, Inge M. ;
Thomma, Bart P. H. J. .
MOLECULAR PLANT PATHOLOGY, 2010, 11 (02) :179-189
[23]   New Necrotic Isolates of Pepino mosaic virus Representing the Ch2 Genotype [J].
Hasiow-Jaroszewska, B. ;
Pospieszny, H. ;
Borodynko, N. .
JOURNAL OF PHYTOPATHOLOGY, 2009, 157 (7-8) :494-496
[24]   1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry [J].
Hu, Yang ;
Li, Cui-Yun ;
Wang, Xiao-Ming ;
Yang, Yong-Hua ;
Zhu, Hai-Liang .
CHEMICAL REVIEWS, 2014, 114 (10) :5572-5610
[25]   1,3,4-Oxadiazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 2: SAR of the C5 position [J].
Johns, Brian A. ;
Weatherhead, Jason G. ;
Allen, Scott H. ;
Thompson, James B. ;
Garvey, Edward P. ;
Foster, Scott A. ;
Jeffrey, Jerry L. ;
Miller, Wayne H. .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (06) :1807-1810
[26]   PEPINO MOSAIC-VIRUS, A NEW POTEXVIRUS FROM PEPINO (SOLANUM-MURICATUM) [J].
JONES, RAC ;
KOENIG, R ;
LESEMANN, DE .
ANNALS OF APPLIED BIOLOGY, 1980, 94 (01) :61-&
[27]  
Jorda C., 2001, Plant Dis, V85
[28]   Tomato Brown Rugose Fruit Virus Contributes to Enhanced Pepino Mosaic Virus Titers in Tomato Plants [J].
Klap, Chen ;
Luria, Neta ;
Smith, Elisheva ;
Hadad, Lior ;
Bakelman, Elena ;
Sela, Noa ;
Belausov, Eduard ;
Lachman, Oded ;
Leibman, Diana ;
Dombrovsky, Aviv .
VIRUSES-BASEL, 2020, 12 (08)
[29]  
Koshelev V.N., 2021, CHEM PROCEEDING, V3, P69, DOI [10.3390/ecsoc-24-08407, DOI 10.3390/ECSOC-24-08407]
[30]   HERBICIDAL ACTIVITY OF 1,3,4-THIADIAZOLE DERIVATIVES [J].
KUBO, H ;
SATO, R ;
HAMURA, I ;
OHI, T .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1970, 18 (01) :60-&