Iron-Catalyzed Dehydrogenative Borylation of Terminal Alkynes

被引：36

作者：

Wei, Duo ^{[1
]}

Carboni, Bertrand ^{[1
]}

Sortais, Jean-Baptiste ^{[1
,2
,3
]}

Darcel, Christophe ^{[1
]}

机构：

[1] Univ Rennes, CNRS, ISCR, UMR 6226, F-35042 Rennes, France

[2] Univ Toulouse, CNRS, LCC, UPS, Toulouse, France

[3] Inst Univ France, 1 Rue Descartes, F-75231 Paris 05, France

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 19期

关键词：

Iron; alkyne; dehydrogenative borylation; pinacolborane; alkynylboronates; C-H BORYLATION; MARKOVNIKOV-SELECTIVE HYDROBORATION; CROSS-COUPLING REACTIONS; ALKENE HYDROBORATION; METAL; FUNCTIONALIZATION; VINYLARENES; COMPLEXES; BONDS; 1,4-HYDROBORATION;

D O I：

10.1002/adsc.201800588

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The catalytic system based on Fe(OTf)(2) (2.5 mol%) and DABCO (1 mol%) selectively promotes the dehydrogenative borylation of both aromatic and aliphatic terminal alkynes to afford alkynylboronate derivatives in the presence of 1 equiv. of pinacolborane at 100 degrees C in toluene. This methodology is applicable to a variety of terminal alkynes (16 examples, yield: 62-93%).

引用

页码：3649 / 3654

页数：6

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