European psychometric validation of the CONTILIFE®:: A Quality of Life questionnaire for urinary incontinence

Objective: To validate 5 language versions (French, Dutch, German, English and Danish) of CONTILIFE(R), a urinary incontinence-specific measure of Quality of Life (QoL). Methods: CONTILIFE(R) was administered to Belgian, Danish, English, French, German, and Dutch women with genuine stress incontinence. The internal consistency, the construct and clinical validity, and the responsiveness to change over time were assessed using standardised procedures. Results: 505 women filled in the CONTILIFE(R) at baseline. Quality of completion was good. The mean number of missing data varied between 0.33 (1.17%) and 0.94 (3.36%) according to the country. Internal consistency was good for all dimensions except for the Effort Activities dimension. Construct validity was good for the Danish, French and pooled sample, and acceptable for English, German and Dutch samples. The distribution of QoL scores differed according to the number of urinary leaks (p < 0.007). 477 women completed the questionnaire twice with a 28-day interval. Responsiveness to clinical improvement was good (\ES\ ≥ 0.50) except for the Sexuality and Well-Being dimensions. Conclusion: In this international European study, CONTILIFE(R) matched the psychometric requirements to be used as a valid, reliable, and sensitive measure of the QoL of the patients. The Daily Activities, Effort Activities, Self-Image and Emotional Consequences dimensions are the most relevant and valid dimensions for purposes of comparison. (C) 2003 Elsevier Science B.V. All fights reserved.