TfNHNHBoc as a SCF3 source for the sulfenylation of indoles

被引：23
作者：
Guo, Jing-Yu
Dai, Rui-Han
Xu, Wen-Cong
Wu, Ruo-Xin
Tian, Shi-Kai [1 ,2 ]
机构：
[1] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Ctr Excellence Mol Synth, Hefei 230026, Anhui, Peoples R China
[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 65期
基金：
中国国家自然科学基金;
关键词：
FREE DIRECT TRIFLUOROMETHYLTHIOLATION; ELECTRON-RICH AROMATICS; S BOND FORMATION; CATALYZED REGIOSELECTIVE THIOLATION; SULFONYL HYDRAZIDES; C-S; ARYLSULFONYL HYDRAZIDES; SODIUM TRIFLUOROMETHANESULFINATE; ASSISTED SYNTHESIS; FUNCTIONALIZATION;
D O I：
10.1039/c8cc04600j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An unprecedented use of trifluoromethanesulfonyl hydrazides as effective SCF3 sources has been established in the sulfenylation of indoles. A range of substituted indoles participated in CuCl-catalyzed oxidative sulfenylation reaction with TfNHNHBoc in the presence of dimethyl sulfoxide to furnish structurally diverse 3-indoyl trifluoromethyl thioethers in moderate to good yields with very high regioselectivity.
引用
收藏
页码：8980 / 8982
页数：3
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