Patient-centered care for left ventricular assist device therapy: current challenges and future directions

被引:14
作者
Breathett, Khadijah [1 ]
Allen, Larry A. [1 ]
Ambardekar, Amrut V. [1 ]
机构
[1] Univ Colorado, Div Cardiol, 12700 E 19th Ave,Campus Box B-139, Aurora, CO 80045 USA
关键词
decision-making; heart failure; left ventricular assist device; mechanical circulatory support; MECHANICAL CIRCULATORY SUPPORT; INTERMACS ANNUAL-REPORT; ADVANCED HEART-FAILURE; CONTINUOUS-FLOW; DESTINATION THERAPY; CLINICAL-OUTCOMES; DECISION-MAKING; DISPARITIES; IMPLANTATION; CAREGIVERS;
D O I
10.1097/HCO.0000000000000279
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of reviewDiscuss the current status and obstacles that need to be overcome in the future to provide patient-centered care with left ventricular assist device (LVAD) therapy.Recent findingsLVADs offer both longer survival and improvements in quality of life for carefully selected patients with inotrope-dependent heart failure. Yet, this technology does not come without significant risk of adverse effects and burdens. Recent observational data comparing LVAD with medical therapy in ambulatory, noninotrope-dependent patients with advanced heart failure suggest that survival may be similar and changes in quality of life may depend on baseline status. As both LVAD technology and medical therapy continue to evolve, there are many unanswered questions regarding the benefits, risks, and burdens of LVAD therapies in less severe heart failure populations.SummaryFurther research is needed to ensure the optimal delivery of LVAD therapy, including improved patient selection, implantation timing, device type, and decision support.Video abstracthttp://links.lww.com/HCO/A32
引用
收藏
页码:313 / 320
页数:8
相关论文
共 41 条
[1]   SEX-DIFFERENCES IN PATIENT ACCEPTANCE OF CARDIAC TRANSPLANT CANDIDACY [J].
AARONSON, KD ;
SCHWARTZ, JS ;
GOIN, JE ;
MANCINI, DM .
CIRCULATION, 1995, 91 (11) :2753-2761
[2]   Use of an Intrapericardial, Continuous-Flow, Centrifugal Pump in Patients Awaiting Heart Transplantation [J].
Aaronson, Keith D. ;
Slaughter, Mark S. ;
Miller, Leslie W. ;
McGee, Edwin C. ;
Cotts, William G. ;
Acker, Michael A. ;
Jessup, Mariell L. ;
Gregoric, Igor D. ;
Loyalka, Pranav ;
Frazier, O. H. ;
Jeevanandam, Valluvan ;
Anderson, Allen S. ;
Kormos, Robert L. ;
Teuteberg, Jeffrey J. ;
Levy, Wayne C. ;
Naftel, David C. ;
Bittman, Richard M. ;
Pagani, Francis D. ;
Hathaway, David R. ;
Boyce, Steven W. .
CIRCULATION, 2012, 125 (25) :3191-+
[3]   Racial Differences in Patients with Left Ventricular Assist Devices [J].
Aggarwal, Ashim ;
Gupta, Ankit ;
Pappas, Pat S. ;
Tatooles, Antone ;
Bhat, Geetha .
ASAIO JOURNAL, 2012, 58 (05) :499-502
[4]   Executive Summary: Decision Making in Advanced Heart Failure A Scientific Statement From the American Heart Association [J].
Allen, Larry A. ;
Stevenson, Lynne W. ;
Grady, Kathleen L. ;
Goldstein, Nathan E. ;
Matlock, Daniel D. ;
Arnold, Robert M. ;
Cook, Nancy R. ;
Felker, G. Michael ;
Francis, Gary S. ;
Hauptman, Paul J. ;
Havranek, Edward P. ;
Krumholz, Harlan M. ;
Mancini, Donna ;
Riegel, Barbara ;
Spertus, John A. .
CIRCULATION, 2012, 125 (15) :1-2
[5]   Changes in Aortic Wall Structure, Composition, and Stiffness With Continuous-Flow Left Ventricular Assist Devices A Pilot Study [J].
Ambardekar, Amrut V. ;
Hunter, Kendall S. ;
Babu, Ashok N. ;
Tuder, Rubin M. ;
Dodson, R. Blair ;
Lindenfeld, JoAnn .
CIRCULATION-HEART FAILURE, 2015, 8 (05) :944-952
[6]   Caregiving for patients requiring left ventricular assistance device support [J].
Baker, Kathy ;
Flattery, Maureen ;
Salyer, Jeanne ;
Haugh, Kathryn H. ;
Maltby, Megan .
HEART & LUNG, 2010, 39 (03) :196-200
[7]   Giving Voice to Patients' and Family Caregivers' Needs in Chronic Heart Failure: Implications for Palliative Care Programs [J].
Bekelman, David B. ;
Nowels, Carolyn T. ;
Retrum, Jessica H. ;
Allen, Larry A. ;
Shakar, Simon ;
Hutt, Evelyn ;
Heyborne, Theresa ;
Main, Deborah S. ;
Kutner, Jean S. .
JOURNAL OF PALLIATIVE MEDICINE, 2011, 14 (12) :1317-1324
[8]   Clinical outcomes for continuous-flow left ventricular assist device patients stratified by pre-operative INTERMACS classification [J].
Boyle, Andrew J. ;
Ascheim, Deborah D. ;
Russo, Mark J. ;
Kormos, Robert L. ;
John, Ranjit ;
Naka, Yoshifumi ;
Gelijns, Annetine C. ;
Hong, Kimberly N. ;
Teuteberg, Jeffrey J. .
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2011, 30 (04) :402-407
[9]   Restoration of Pulsatile Flow Reduces Sympathetic Nerve Activity Among Individuals With Continuous-Flow Left Ventricular Assist Devices [J].
Cornwell, William K. ;
Tarumi, Takashi ;
Stickford, Abigail ;
Lawley, Justin ;
Roberts, Monique ;
Parker, Rosemary ;
Fitzsimmons, Catherine ;
Kibe, Julius ;
Ayers, Colby ;
Markham, David ;
Drazner, Mark H. ;
Fu, Qi ;
Levine, Benjamin D. .
CIRCULATION, 2015, 132 (24) :2316-2322
[10]   Effect of pulsatile and nonpulsatile flow on cerebral perfusion in patients with left ventricular assist devices [J].
Cornwell, William K., III ;
Tarumi, Takashi ;
Aengevaeren, Vincent L. ;
Ayers, Colby ;
Divanji, Punag ;
Fu, Qi ;
Palmer, Dean ;
Drazner, Mark H. ;
Meyer, Dan M. ;
Bethea, Brian T. ;
Hastings, Jeffrey L. ;
Fujimoto, Naoki ;
Shibata, Shigeki ;
Zhang, Rong ;
Markham, David W. ;
Levine, Benjamin D. .
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2014, 33 (12) :1295-1303