Evaluation of disk diffusion and Etest compared to broth microdilution for antifungal susceptibility testing of posaconazole against clinical isolates of filamentous fungi

被引:20
作者
Messer, Shawn A.
Diekema, Daniel J.
Hollis, Richard J.
Boyken, Linda B.
Tendolkar, Shailesh
Kroeger, Jennifer
Pfaller, Michael A.
机构
[1] Univ Iowa, Carver Coll Med, Dept Pathol, Iowa City, IA 52242 USA
[2] Univ Iowa, Carver Coll Med, Dept Internal Med, Iowa City, IA 52242 USA
[3] Univ Iowa, Carver Coll Med, Dept Epidemiol, Iowa City, IA 52242 USA
[4] Univ Iowa, Coll Publ Hlth, Iowa City, IA 52242 USA
关键词
D O I
10.1128/JCM.02450-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We performed Etest, disk diffusion, and broth microdillution susceptibility testing of posaconazole against 146 clinical isolates of filamentous fungi. By using provisional breakpoints for comparison purposes only, categorical agreement between the results of the agar-based methods and those of broth microdilution were 96 to 98%, with no very major errors. These agar-based methods hold promise as simple and reliable methods for determining the posaconazole susceptibilities of filamentous fungi.
引用
收藏
页码:1322 / 1324
页数:3
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