Modulation of thermal pain-related brain activity with virtual reality: evidence from fMRI

被引：234
作者：
Hoffman, HG
Richards, TL
Coda, B
Bills, AR
Blough, D
Richards, AL
Sharar, SR
机构：
[1] Univ Washington, Human Interface Technol Lab, Seattle, WA 98195 USA
[2] Univ Washington, Dept Radiol, Seattle, WA 98195 USA
[3] Univ Washington, Dept Pharm, Seattle, WA 98195 USA
[4] Univ Washington, Dept Anesthesiol, Seattle, WA 98104 USA
来源：
NEUROREPORT | 2004年 / 15卷 / 08期
关键词：
analgesia; anterior cingulate cortex; fMRI; pain; somatosensory cortex; virtual reality;
D O I：
10.1097/01.wnr.0000127826.73576.91
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
This study investigated the neural correlates of virtual reality analgesia. Virtual reality significantly reduced subjective pain ratings (i.e. analgesia). Using fMRI, pain-related brain activity was measured for each participant during conditions of no virtual reality and during virtual reality (order randomized). As predicted, virtual reality significantly reduced pain-related brain activity in all five regions of interest; the anterior cingulate cortex, primary and secondary somatosensory cortex, insula, and thalamus (p<0.002, corrected). Results showed direct modulation of human brain pain responses by virtual reality distraction.
引用
收藏
页码：1245 / 1248
页数：4
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