COVID-19 and Hypertension: The What, the Why, and the How

被引：39
|
作者：
Muhamad, Shah-Abas [1 ]
Ugusman, Azizah [1 ]
Kumar, Jaya [1 ]
Skiba, Dominik [2 ]
Hamid, Adila A. [1 ]
Aminuddin, Amilia [1 ]
机构：
[1] Univ Kebangsaan Malaysia, Dept Physiol, Fac Med, Med Ctr, Kuala Lumpur, Malaysia
[2] Polish Acad Sci, Inst Genet & Anim Biotechnol, Magdalenka, Poland
来源：
FRONTIERS IN PHYSIOLOGY | 2021年 / 12卷
关键词：
coronavirus; COVID-19; SARS-CoV-2; hypertension; endothelial dysfunction; renin angiotensin system; angiotensin converting enzyme 2; ANGIOTENSIN-CONVERTING ENZYME; CYTOKINE STORM; CLINICAL CHARACTERISTICS; ENDOTHELIAL DYSFUNCTION; SARS CORONAVIRUS; ACE2; RECEPTOR; SYSTEM; WUHAN; INFLAMMATION;
D O I：
10.3389/fphys.2021.665064
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
It has been a year since the coronavirus disease 2019 (COVID-19) was declared pandemic and wreak havoc worldwide. Despite meticulous research has been done in this period, there are still much to be learn from this novel coronavirus. Globally, observational studies have seen that majority of the patients with COVID-19 have preexisting hypertension. This raises the question about the possible relationship between COVID-19 and hypertension. This review summarizes the current understanding of the link between hypertension and COVID-19 and its underlying mechanisms.
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页数：11
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