A Triad of Crystals Sheds Light on MDGA Interference with Neuroligation

被引：9

作者：

Thoumine, Olivier ^{[1
]}

Marchot, Pascale ^{[2
]}

机构：

[1] Univ Bordeaux, CNRS, UMR 5297, Interdisciplinary Inst Neurosci, F-33000 Bordeaux, France

[2] Aix Marseille Univ, Architecture & Fonct Macromol Biol Lab, Fac Sci Luminy, CNRS, F-13288 Marseille, France

来源：

NEURON | 2017年 / 95卷 / 04期

关键词：

INHIBITORY SYNAPSE DEVELOPMENT; STRUCTURAL INSIGHTS;

D O I：

10.1016/j.neuron.2017.08.001

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Neurexins and neuroligins form trans-synaptic complexes that promote synapse development. In this issue of Neuron, Aricescu and colleagues (Elegheert et al., 2017) complement and strengthen two recent reports by the Kim and Rudenko teams (Kimet al., 2017; Gangwar et al., 2017) to dissect the molecular determinants by which MDGAs challenge the neurexin-neuroligin partnership.

引用

页码：729 / 732

页数：5

共 9 条

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