Isolated Conjunctival Inflammation as a Manifestation of IgG4-Related Disease

被引：6

作者：

Li, Ang ^{[1
]}

Plesec, Thomas P. ^{[2
]}

Mileti, Linda ^{[3
]}

Singh, Arun D. ^{[1
]}

机构：

[1] Cole Eye Inst, Dept Ophthalmol, Cleveland, OH 44106 USA

[2] Cleveland Clin, Dept Anat Pathol, Cleveland, OH 44106 USA

[3] Cleveland Clin, Dept Rheumatol, Cleveland, OH 44106 USA

来源：

CORNEA | 2018年 / 37卷 / 09期

关键词：

conjunctival inflammation; IgG4-related disease; conjunctival IgG4; DIAGNOSTIC-CRITERIA; STATEMENT; LESIONS;

D O I：

10.1097/ICO.0000000000001638

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose:To report a unique case of isolated conjunctival inflammation from IgG4-related disease (IgG4-RD) confirmed by pathology.Methods:A single interventional case of conjunctival IgG4-RD.Results:A 63-year-old woman presented with a chronic, solitary, vascularized, tan-colored, and raised conjunctival lesion measuring 7.5 x 8.0 x 1.2 mm located at the temporal bulbar conjunctiva. An excisional biopsy was diagnostic of IgG4-RD based on the classic fibrosis pattern, 120 IgG4-positive plasma cells per high-power field, and an overwhelming majority of IgG4-positive cells among IgG plasma cells. No orbital or systemic involvement was found on clinical examination, imaging, and laboratory workup. The serum IgG4 level was normal (87.1 mg/dL). The patient was free of recurrence at 6-month follow-up.Conclusions:Isolated conjunctival inflammation without orbital involvement can be a presentation of IgG4-RD.

引用

页码：1182 / 1184

页数：3

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