Iridium(I) N-Heterocyclic Carbene (NHC)/Phosphine Catalysts for Mild and Chemoselective Hydrogenation Processes

被引：33

作者：

Kerr, William J. ^{[1
]}

Mudd, Richard J. ^{[1
]}

Brown, Jack A. ^{[2
]}

机构：

[1] Univ Strathclyde, WestCHEM, Dept Pure & Appl Chem, 295 Cathedral St, Glasgow G1 1XL, Lanark, Scotland

[2] GlaxoSmithKline R&D, Med Res Ctr, Gunnels Wood Rd, Stevenage SG1 2NY, Herts, England

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2016年 / 22卷 / 14期

关键词：

chemoselectivity; homogeneous catalysis; hydrogenation; iridium; reduction; C-H ACTIVATION; HOMOGENEOUS HYDROGENATION; ISOTOPE-EXCHANGE; COMPLEXES; STEREOCONTROL; ACETYLENES; OLEFINS; RHODIUM; LIGAND;

D O I：

10.1002/chem.201504825

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The directed chemoselective hydrogenation of olefins has been established by using iridium(I) catalysts, which feature a tuned NHC/phosphine ligand combination. This selective reduction process has been demonstrated in a wide array of solvents, including more environmentally acceptable media, also allowing further refinement of hydrogenation selectivity.

引用

页码：4738 / 4742

页数：5

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