UK national guidelines on the management of syphilis 2015

被引：195

作者：

Kingston, M. ^{[1
]}

French, P. ^{[2
]}

Higgins, S. ^{[3
]}

McQuillan, O. ^{[1
]}

Sukthankar, A. ^{[1
]}

Stott, C. ^{[1
]}

McBrien, B. ^{[1
]}

Tipple, C. ^{[4
]}

Turner, A. ^{[5
]}

Sullivan, A. K.

Radcliffe, Keith ^{[6
]}

Cousins, Darren ^{[6
]}

FitzGerald, Mark ^{[6
]}

Fisher, Martin ^{[6
]}

Grover, Deepa ^{[6
]}

Higgins, Stephen ^{[6
]}

Kingston, Margaret ^{[6
]}

Rayment, Michael ^{[6
]}

Sullivan, Ann ^{[6
]}

机构：

[1] Manchester Ctr Sexual Hlth, 280 Upper Brook St, Manchester M13 0FH, Lancs, England

[2] Mortimer Market Ctr, London, England

[3] North Manchester Gen Hosp, Manchester, Lancs, England

[4] Imperial Coll Hlth Care NHS Trust, Jefferiss Wing Ctr Sexual Hlth, London, England

[5] Manchester Royal Infirm, Publ Hlth England, Clin Virol Lab, Oxford Rd, Manchester M13 9WL, Lancs, England

[6] British Assoc Sexual Hlth & HIV, Clin Effectiveness Grp, Macclesfield, Cheshire, England

来源：

INTERNATIONAL JOURNAL OF STD & AIDS | 2016年 / 27卷 / 06期

关键词：

Syphilis; Treponema pallidum; diagnosis; treatment; sexually transmitted infections; guideline; BENZATHINE PENICILLIN-G; JARISCH-HERXHEIMER REACTION; HIV-INFECTED PATIENTS; REAL-TIME PCR; CEREBROSPINAL-FLUID; TREPONEMA-PALLIDUM; CONGENITAL-SYPHILIS; CEFTRIAXONE THERAPY; SECONDARY SYPHILIS; MATERNAL TREATMENT;

D O I：

10.1177/0956462415624059

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

These guidelines are an update for 2015 of the 2008 UK guidelines for the management of syphilis. The writing group have piloted the new BASHH guideline methodology, notably using the GRADE system for assessing evidence and making recommendations. We have made significant changes to the recommendations for screening infants born to mothers with positive syphilis serology and to facilitate accurate and timely communication between the teams caring for mother and baby we have developed a birth plan. Procaine penicillin is now an alternative, not preferred treatment, for all stages of syphilis except neurosyphilis, but the length of treatment for this is shortened. Other changes are summarised at the start of the guideline.

引用

页码：421 / 446

页数：26

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