The CRISPR-Cas9 system in Neisseria spp

被引:11
|
作者
Zhang, Yan [1 ,2 ]
机构
[1] Univ Massachusetts, Sch Med, RNA Therapeut Inst, Worcester, MA 01605 USA
[2] Univ Michigan, Dept Biol Chem, Ann Arbor, MI 48109 USA
来源
PATHOGENS AND DISEASE | 2017年 / 75卷 / 04期
关键词
CRISPR-Cas9; genome engineering; RNA-guided adaptive interference; Neisseria spp; CAS ADAPTIVE IMMUNITY; RNA-GUIDED ENDONUCLEASE; TARGET DNA RECOGNITION; ESCHERICHIA-COLI; NATURAL TRANSFORMATION; SPACER ACQUISITION; BACTERIAL IMMUNITY; CRISPR/CAS SYSTEM; GENE-REGULATION; FOREIGN DNA;
D O I
10.1093/femspd/ftx036
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Bacteria and archaea possess numerous defense systems to combat viral infections and other mobile genetic elements. Uniquely among these, CRISPR-Cas (clustered, regularly interspaced short palindromic repeats-CRISPR associated) provides adaptive genetic interference against foreign nucleic acids. Here we review recent advances on the CRISPR-Cas9 system in Neisseria spp, with a focus on its biological functions in genetic transfer, its mechanistic features that establish new paradigms and its technological applications in eukaryotic genome engineering.
引用
收藏
页数:10
相关论文
共 50 条
  • [1] CRISPR-Cas9 System: Opportunities and Concerns
    Vasiliou, Stella K.
    Diamandis, Eleftherios P.
    Church, George M.
    Greely, Henry T.
    Baylis, Francoise
    Thompson, Charis
    Schmitt-Ulms, Gerold
    CLINICAL CHEMISTRY, 2016, 62 (10) : 1304 - 1311
  • [2] CRISPR-Cas9 System and Its Application
    Benesova, Eva
    CHEMICKE LISTY, 2020, 114 (09): : 586 - 590
  • [3] Target specificity of the CRISPR-Cas9 system
    Xuebing Wu
    Andrea JKriz
    Phillip ASharp
    Quantitative Biology, 2014, 2 (02) : 59 - 70
  • [4] The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells
    Lee, Ciaran M.
    Cradick, Thomas J.
    Bao, Gang
    MOLECULAR THERAPY, 2016, 24 (03) : 645 - 654
  • [5] Programmable RNA Cleavage and Recognition by a Natural CRISPR-Cas9 System from Neisseria meningitidis
    Rousseau, Beth A.
    Hou, Zhonggang
    Gramelspacher, Max J.
    Zhang, Yan
    MOLECULAR CELL, 2018, 69 (05) : 906 - +
  • [6] Implementation of the CRISPR-Cas9 system in fission yeast
    Jacobs, Jake Z.
    Ciccaglione, Keith M.
    Tournier, Vincent
    Zaratiegui, Mikel
    NATURE COMMUNICATIONS, 2014, 5
  • [7] Expanding application of CRISPR-Cas9 system in microorganisms
    Zhao, Jing
    Fang, Huan
    Zhang, Dawei
    SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2020, 5 (04) : 269 - 276
  • [8] Implementation of the CRISPR-Cas9 system in fission yeast
    Jake Z. Jacobs
    Keith M. Ciccaglione
    Vincent Tournier
    Mikel Zaratiegui
    Nature Communications, 5
  • [9] Genome engineering using the CRISPR-Cas9 system
    F Ann Ran
    Patrick D Hsu
    Jason Wright
    Vineeta Agarwala
    David A Scott
    Feng Zhang
    Nature Protocols, 2013, 8 : 2281 - 2308
  • [10] Applications of the CRISPR-Cas9 system in cancer biology
    Sanchez-Rivera, Francisco J.
    Jacks, Tyler
    NATURE REVIEWS CANCER, 2015, 15 (07) : 387 - 395