Chemical Constituents of the Roots of Lindera chunii

被引:5
作者
Li, Yuxian [1 ]
Wen, Songsong [2 ]
Yang, Hai [3 ]
Wang, Yan [4 ]
Wu, Ying [4 ]
Sun, Zhenliang [5 ]
机构
[1] Jilin Agr Sci & Technol Coll, Tradit Chinese Med Dept, Jilin 132101, Jilin, Peoples R China
[2] Shandong Inst Food & Drug Control, Jinan 250101, Shandong, Peoples R China
[3] Qingdao Univ, Affiliated Hosp 2, Dept Pharm, Qingdao 266042, Shandong, Peoples R China
[4] Shanghai Putuo Dist Liqun Hosp, 910 Tao Pu Rd, Shanghai 200333, Peoples R China
[5] Shanghai Univ Med & Hlth Sci, Peoples Hosp 6, South Campus, Shanghai 201499, Peoples R China
关键词
Lindera chunii; sesquiterpenoid dimer; butanolide; CYTOTOXIC BUTANOLIDES;
D O I
10.1007/s10600-019-02896-0
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new sesquiterpenoid dimer, lindenanolide I (1), and two new butanolides, (2E,3R,4S)-2-dodecylinene-3-hydroxy-4-ethoxy-4-methylbutanolide (3) and (2E,3R,4S)-2-tetradecylinene-3-hydroxy-4-ethoxy-4-methylbutanolide (4), together with five known compounds (2, 5-8), were isolated from the roots of Lindera chunii. The structures of these compounds were elucidated on the basis of extensive spectroscopic analysis and by comparison of the data with those of related secondary metabolites. The absolute configuration of 1 was identified by electronic circular dichroism (ECD) analysis. Compounds 5-8 were isolated from this plant for the first time.
引用
收藏
页码:1069 / 1072
页数:4
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