Application of modified stokes expression to model the behavior of expanded beds with feed streams containing E-coli homogenates

被引:2
作者
Chae, YR
Yoon, YJ
Ryu, K [1 ]
机构
[1] Univ Ulsan, Sch Chem Engn & Bioengn, Ulsan 680749, South Korea
[2] Ewha Womans Univ, Dept Chem, Seoul 120750, South Korea
[3] Ewha Womans Univ, Div Nano Sci, Seoul 120750, South Korea
关键词
expanded bed; modeling; Stokes expression; cell homogenates;
D O I
10.1007/BF02942352
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
To model the behavior of expanded beds with aqueous feed streams containing different amounts of glycerol, we previously developed a modified Stokes expression that correlates the terminal settling velocity of a particle of a solution with the properties of the particle (particle diameter and density) and the solution (density and viscosity). Two empirical parameters, the effective diameter of the poly-disperse resins for protein adsorption and an exponent of non-unity for (rho(rho)-rho)/mu term, are introduced in the modified Stokes expression. We applied the same type of the modified Stokes expression in combination with the Richardson-Zaki correlation to the published results [1], and found that the expansions of the beds with feed streams containing different amounts of E. coli homogenates can also be successfully described.
引用
收藏
页码:323 / 325
页数:3
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