The clinical value of squamous cell carcinoma antigen in patients irradiated for locally advanced cancer of the head and neck

被引：0
|
作者：
Micke, O
Bruns, F
Schäfer, U
Horst, E
Büntzel, J
Willich, N
机构：
[1] Univ Klinikum Munster, Klin & Poliklin Strahlentherapie Radioonkol, D-48129 Munster, Germany
[2] Sudharz Krankenhaus Nordhausen GmbH, HNO Klin, D-99734 Nordhausen, Germany
来源：
ANTICANCER RESEARCH | 2003年 / 23卷 / 2A期
关键词：
SCC; squamous cell carcinoma antigen; head and neck cancer; radiochemotherapy; radiotherapy;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Purpose: This study examines the value of squamous cell cancer (SCC) antigen in patients irradiated for locally advanced cancer of the head and neck. Materials and Methods: In 20 patients (group A) treated with radiochemotherapy and in 20 patients (group B) receiving postoperative it-radiation serum SCC values were investigated. Results: The pretreatment SCC level was 1.6 ng/ml in group A and 1.3 ng/ml in group B. In group A 15 % had elevated serum SCC levels above the cut-off level. In group B there were 10 %. During follow-up (median 20 months),. 10 patients in group A and 8 in group B suffered from a recurrent or progressing disease. Of these 20 % in group A and 12.5 % in group B had elevated SCC levels. Conclusion: Our results suggest that, in the described patient groups, SCC is probably of low value for tumor diagnosis and follow-up.
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页码：907 / 911
页数：5
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