Aberrant methylation of gene promoters in cancer - Concepts, misconcepts, and promise

被引：111
作者：
Baylin, SB
Belinsky, SA
Herman, JG
机构：
[1] Johns Hopkins Med Inst, Baltimore, MD 21205 USA
[2] Ctr Comprehens Canc, Baltimore, MD USA
[3] Lovelace Resp Res Inst, Albuquerque, NM USA
来源：
JOURNAL OF THE NATIONAL CANCER INSTITUTE | 2000年 / 92卷 / 18期
关键词：
D O I：
10.1093/jnci/92.18.1460
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：1460 / 1461
页数：2
相关论文
共 17 条
  • [1] DNA hypermethylation in tumorigenesis - epigenetics joins genetics
    Baylin, SB
    Herman, JG
    [J]. TRENDS IN GENETICS, 2000, 16 (04) : 168 - 174
  • [2] Methylation-induced repression - Belts, braces, and chromatin
    Bird, AP
    Wolffe, AP
    [J]. CELL, 1999, 99 (05) : 451 - 454
  • [3] Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
    Cameron, EE
    Bachman, KE
    Myöhänen, S
    Herman, JG
    Baylin, SB
    [J]. NATURE GENETICS, 1999, 21 (01) : 103 - 107
  • [4] Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
    Esteller, M
    Silva, JM
    Dominguez, G
    Bonilla, F
    Matias-Guiu, X
    Lerma, E
    Bussaglia, E
    Prat, J
    Harkes, IC
    Repasky, EA
    Gabrielson, E
    Schutte, M
    Baylin, SB
    Herman, JG
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (07): : 564 - 569
  • [5] BRCA1 and E-cadherin promoter hypermethylation and gene inactivation in cancer-association or mechanism?
    Fearon, ER
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (07): : 515 - 517
  • [6] Facile detection of mitochondrial DNA mutations in tumors and bodily fluids
    Fliss, MS
    Usadel, H
    Cabellero, OL
    Wu, L
    Buta, MR
    Eleff, SM
    Jen, J
    Sidransky, D
    [J]. SCIENCE, 2000, 287 (5460) : 2017 - 2019
  • [7] DNA methyltransferase Dnmt1 associates with histone deacetylase activity
    Fuks, F
    Burgers, WA
    Brehm, A
    Hughes-Davies, L
    Kouzarides, T
    [J]. NATURE GENETICS, 2000, 24 (01) : 88 - 91
  • [8] Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
    Herman, JG
    Umar, A
    Polyak, K
    Graff, JR
    Ahuja, N
    Issa, JPJ
    Markowitz, S
    Willson, JKV
    Hamilton, SR
    Kinzler, KW
    Kane, MF
    Kolodner, RD
    Vogelstein, B
    Kunkel, TA
    Baylin, SB
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (12) : 6870 - 6875
  • [9] Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
    Herman, JG
    Graff, JR
    Myohanen, S
    Nelkin, BD
    Baylin, SB
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (18) : 9821 - 9826
  • [10] DAP kinase links the control of apoptosis to metastasis
    Inbal, B
    Cohen, O
    PolakCharcon, S
    Kopolovic, J
    Vadai, E
    Eisenbach, L
    Kimchi, A
    [J]. NATURE, 1997, 390 (6656) : 180 - 184
12