A novel lupene-type triterpenic glucoside from the leaves of Clerodendrum inerme

被引：17

作者：

Parveen, Mehtab ^{[1
]}

Khanam, Zakia ^{[1
]}

Ali, Mohammad ^{[2
]}

Rahman, Syed Ziaur ^{[3
]}

机构：

[1] Aligarh Muslim Univ, Dept Chem, Aligarh 202002, Uttar Pradesh, India

[2] Fac Pharm, Dept Pharmacognosy & Phytochem, New Delhi 110062, India

[3] Aligarh Muslim Univ, Jawaharlal Nehru Med Univ, Dept Pharmacol, Aligarh 202002, Uttar Pradesh, India

来源：

NATURAL PRODUCT RESEARCH | 2010年 / 24卷 / 02期

关键词：

Clerodendrum inerme; triterpenic glucoside; lup-1; 5; 20(29)-trien-3-O--D-glucopyranoside; n-octacosane; friedelin; -amyrin; antinociceptive activity; NEOCLERODANE DITERPENOIDS; ACID-PHOSPHATASE; CHOLINESTERASE; CONSTITUENTS; VERBENACEAE; PLANTS; RATS;

D O I：

10.1080/14786410902975566

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new triterpenic glucoside, lup-1,5,20(29)-trien-3-O--D-glucopyranoside (4), along with three known phytoconstituents: n-octacosane, friedelin and -amyrin, has been isolated from the leaves of Clerodendrum inerme (L.) Gaertn. (Verbenaceae). Structure elucidation was carried out on the basis of chemical and physical evidence (IR, 1H-NMR, 13C-NMR, DEPT and MS spectra). The alcoholic and aqueous extracts of the leaves of C. inerme showed significant antinociceptive activity in analgaesiometer tests.

引用

页码：167 / 176

页数：10

共 29 条

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[2]

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[3]

[Anonymous], 2001, The Wealth Of India, V2, P67

[4]

Basappa H., 2002, Indian Journal of Plant Protection, V30, P187