Recovery from Acute Kidney Injury: The Role of Biomarkers

被引:18
作者
Endre, Zoltan H. [1 ,2 ,3 ,4 ]
机构
[1] Prince Wales Hosp, Dept Nephrol, Sydney, NSW 2031, Australia
[2] Univ New S Wales, Prince Wales Clin Sch, Sydney, NSW, Australia
[3] Univ Queensland, Sch Med, Brisbane, Qld, Australia
[4] Univ Otago, Dept Med, Christchurch, New Zealand
来源
NEPHRON CLINICAL PRACTICE | 2014年 / 127卷 / 1-4期
关键词
Acute kidney injury; Biomarkers; Cardiac surgery; Critical care; Transplantation; CRITICALLY-ILL PATIENTS; URINARY BIOMARKERS; PREDICT; PROGRESSION; MARKER;
D O I
10.1159/000363678
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Establishing the prognosis for recovery has enormous clinical implications. The appropriate definition of renal recovery depends on the stage of acute kidney injury (AKI). As definitions of AKI have broadened to encompass small increases in serum creatinine, definitions of recovery have broadened from becoming dialysis independent to full recovery of baseline glomerular function. Damage and functional biomarkers can assist in the prediction of recovery. Both decreases in damage biomarker concentration and increases in kidney function predict recovery. Structural biomarkers that directly predict recovery are awaited. (C) 2014 S. Karger AG, Basel
引用
收藏
页码:101 / 105
页数:5
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