Recent Advances on the Green Synthesis and Antioxidant Activities of Pyrazoles

被引:25
作者
Dias, Daiane [1 ]
Pacheco, Bruna S. [2 ]
Cunico, Wilson [2 ]
Pizzuti, Lucas [3 ]
Pereira, Claudio M. P. [2 ,4 ]
机构
[1] Fundacao Univ Fed Rio Grande, Chem & Food Sch, BR-96203900 Rio Grande, RS, Brazil
[2] Univ Fed Pelotas, Postgrad Program Biochem & Bioprospect, Pelotas, RS, Brazil
[3] Fed Univ Grande Dourados, Mato Grosso, MS, Brazil
[4] Univ Fed Pelotas, Lab Lipid & Bioorgan, Pelotas, RS, Brazil
关键词
Antioxidant activities; green chemistry; pyrazoles; ANTI-HCV; DERIVATIVES; ANTITUMOR; ANTIMICROBIALS; DESIGN; BIS;
D O I
10.2174/1389557515666150101102606
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Pyrazoles have a representative history in medicinal chemistry. These nucleuses, molecules of synthetic origin, constitute a group of nitrogen heterocyclic compounds. Available literature particularly shows a variety of pyrazoles with antioxidant effect. In this connection, this review describes the advances on the green synthesis of pyrazoles with antioxidant activity, mainly covering the data published over the last seven years (2008-2014).
引用
收藏
页码:1078 / 1092
页数:15
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