Obstructive Sleep Apnea and Type 2 Diabetes in Older Adults

被引：22
作者：
Moon, Karoline [1 ]
Punjabi, Naresh M. [1 ]
Aurora, R. Nisha [1 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Div Pulm & Crit Care Med, 5501 Hopkins Bayview Circle, Baltimore, MD 21224 USA
来源：
CLINICS IN GERIATRIC MEDICINE | 2015年 / 31卷 / 01期
基金：
美国国家卫生研究院;
关键词：
Obstructive sleep apnea; Central sleep apnea; Type; 2; diabetes; Aging; CARDIOVASCULAR-DISEASE; PREVALENCE; AGE; EPIDEMIOLOGY; IMPACT; MEN; RESPONSES; MELLITUS; HYPOXIA; RISK;
D O I：
10.1016/j.cger.2014.08.023
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Both obstructive sleep apnea (OSA) and type 2 diabetes mellitus are commonly seen in older adults. Over the last decade, there has been increasing recognition that OSA is highly prevalent in persons with type 2 diabetes and related metabolic conditions such as insulin resistance and glucose intolerance. Intermittent hypoxemia and recurrent arousals in OSA trigger a repertoire of pathophysiological events, which can in turn alter glucose homeostasis and possibly increase the risk for type 2 diabetes. Conversely, there is evidence that type 2 diabetes may alter the progression and expression of sleep-disordered breathing.
引用
收藏
页码：139 / 147
页数：9
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