Obstructive Sleep Apnea and Type 2 Diabetes in Older Adults

被引：24

作者：

Moon, Karoline ^{[1
]}

Punjabi, Naresh M. ^{[1
]}

Aurora, R. Nisha ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Div Pulm & Crit Care Med, 5501 Hopkins Bayview Circle, Baltimore, MD 21224 USA

来源：

CLINICS IN GERIATRIC MEDICINE | 2015年 / 31卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Obstructive sleep apnea; Central sleep apnea; Type; 2; diabetes; Aging; CARDIOVASCULAR-DISEASE; PREVALENCE; AGE; EPIDEMIOLOGY; IMPACT; MEN; RESPONSES; MELLITUS; HYPOXIA; RISK;

D O I：

10.1016/j.cger.2014.08.023

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Both obstructive sleep apnea (OSA) and type 2 diabetes mellitus are commonly seen in older adults. Over the last decade, there has been increasing recognition that OSA is highly prevalent in persons with type 2 diabetes and related metabolic conditions such as insulin resistance and glucose intolerance. Intermittent hypoxemia and recurrent arousals in OSA trigger a repertoire of pathophysiological events, which can in turn alter glucose homeostasis and possibly increase the risk for type 2 diabetes. Conversely, there is evidence that type 2 diabetes may alter the progression and expression of sleep-disordered breathing.

引用

页码：139 / 147

页数：9

共 45 条

[1] An update on the etiology and epidemiology of diabetes mellitus [J].

Adeghate, Ernest ;

Schattner, Peter ;

Dunn, Earl .

DIABETES MELLITUS AND ITS COMPLICATIONS: MOLECULAR MECHANISMS, EPIDEMIOLOGY, AND CLINICAL MEDICINE, 2006, 1084 :1-29

[2]

Amer Diabet Assoc, 2011, DIABETES CARE, V34, pS11, DOI [10.2337/dc11-S062, 10.2337/dc14-S081, 10.2337/dc11-S011, 10.2337/dc13-S067, 10.2337/dc12-s011, 10.2337/dc10-S011, 10.2337/dc10-S062, 10.2337/dc13-S011, 10.2337/dc12-s064]

[3]

Ancoli-Israel S, 2005, J CLIN PSYCHIAT, V66, P24

[4] Long-term follow-up of sleep disordered breathing in older adults [J].