Combined use of sirolimus and voriconazole in renal transplantation: A report of two cases

被引：36
作者：
Mathis, AS [1 ]
Shah, NK [1 ]
Friedman, GS [1 ]
机构：
[1] St Barnabas Hosp, Dept Pharm, Livingston, NJ 07039 USA
来源：
TRANSPLANTATION PROCEEDINGS | 2004年 / 36卷 / 09期
关键词：
D O I：
10.1016/j.transproceed.2004.09.043
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Voriconazole is currently contraindicated for use with sirolimus. We report our experience with voriconazole/sirolimus in two renal transplant recipients. To our knowledge, this is the first experience with voriconazole/sirolimus. An interaction requiring a 75% to 87.5% sirolimus dose reduction was noted, but goal trough levels and clinical tolerability were achieved.
引用
收藏
页码：2708 / 2709
页数：2
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