Norneolignans from the roots of Clitoria ternatea L.

被引：12

作者：

Vasisht, Karan ^{[1
]}

Dhobi, Mahaveer ^{[1
]}

Khullar, Sadhika ^{[2
]}

Mandal, Sanjay K. ^{[2
]}

Karan, Maninder ^{[1
]}

机构：

[1] Panjab Univ, Univ Inst Pharmaceut Sci, UGC Ctr Adv Study, Chandigarh 160014, India

[2] Indian Inst Sci Educ & Res, Dept Chem Sci, Sect 81, Manauli PO, Mohali 140306, Punjab, India

来源：

TETRAHEDRON LETTERS | 2016年 / 57卷 / 16期

关键词：

Clitoria ternatea; Clitorienolactones; Norneolignan; Memory enhancer; ANTHOCYANINS; NEOLIGNANS; LIGNANS; FLOWERS; RATS; A3;

D O I：

10.1016/j.tetlet.2016.03.024

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new norneolignans, the clitorienolactones A-C along with a known triterpenoid, taraxerol were isolated from the roots of Clitoria ternatea L. The structures of clitorienolactones A-C were established on the basis of UV, IR, 1D and 2D NMR, and HRESIMS analyses and were further confirmed by X-ray crystallographic analysis of clitorienolactone A. The clitorienolactones A and B possess memory enhancing and the acetylcholinesterase inhibitory activities. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：1758 / 1762

页数：5

共 34 条

[1] Studies on Krameriaceae .11. Lignans and neolignans from Krameria parvifolia [J].

Achenbach, H ;

Utz, W ;

Lozano, B ;

Touche, EMG ;

Moreno, S .

PHYTOCHEMISTRY, 1996, 43 (05) :1093-1095

[2]

BANERJEE S K, 1963, Bull Calcutta Sch Trop Med, V11, P106

[3]

BANERJEE S K, 1964, Bull Calcutta Sch Trop Med, V12, P23

[4]

Chunekar K. C., 2002, BHAVAPRAKASA NIGHANT, P342

[5]

Debnath N.B., 1975, J I CHEM INDIA, V47, P253

[6] A NEW AND RAPID COLORIMETRIC DETERMINATION OF ACETYLCHOLINESTERASE ACTIVITY [J].

ELLMAN, GL ;

COURTNEY, KD ;

ANDRES, V ;

FEATHERSTONE, RM .

BIOCHEMICAL PHARMACOLOGY, 1961, 7 (02) :88-&

[7] Revised section F: Natural products and related compounds - IUPAC Recommendations 1999) [J].

Giles, PM .

PURE AND APPLIED CHEMISTRY, 1999, 71 (04) :587-643

[8]

GUPTA R K, 1968, Indian Journal of Pharmacy, V30, P167

[9] Clitoria ternatea and the CNS [J].

Jain, NN ;

Ohal, CC ;

Shroff, SK ;

Bhutada, RH ;

Somani, RS ;

Kasture, VS ;

Kasture, SB .

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2003, 75 (03) :529-536

[10] CHEMICAL EXAMINATION OF CLITORIA-TERNATEA SEEDS [J].

JOSHI, SS ;

SHRIVASTAVA, RK ;

SHRIVASTAVA, DK .

JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1981, 58 (06) :714-715

← 1 2 3 4 →