Geographic disparities in COVID-19 case rates are not reflected in seropositivity rates using a neighborhood survey in Chicago

被引：9

作者：

Mustanski, Brian ^{[1
,2
]}

Saber, Rana ^{[1
]}

Ryan, Daniel T. ^{[1
]}

Benbow, Nanette ^{[3
]}

Madkins, Krystal ^{[1
]}

Hayford, Christina ^{[4
]}

Newcomb, Michael E. ^{[1
,2
]}

Schrock, Joshua M. ^{[1
]}

Vaught, Lauren A. ^{[5
]}

Reiser, Nina L. ^{[5
]}

Velez, Matthew P. ^{[5
]}

Hsieh, Ryan R. ^{[5
]}

Demonbreun, Alexis R. ^{[5
,6
]}

D'Aquila, Richard ^{[4
]}

McNally, Elizabeth M. ^{[5
]}

McDade, Thomas W. ^{[7
,8
]}

机构：

[1] Northwestern Univ, Inst Sexual & Gender Minor Hlth & Wellbeing, Chicago, IL 60611 USA

[2] Northwestern Univ, Dept Med Social Sci, Feinberg Sch Med, Chicago, IL 60611 USA

[3] Northwestern Univ, Dept Psychiat & Behav Sci, Feinberg Sch Med, Chicago, IL 60611 USA

[4] Northwestern Univ, Dept Med, Div Infect Dis, Feinberg Sch Med, Chicago, IL 60611 USA

[5] Northwestern Univ, Ctr Genet Med, Feinberg Sch Med, Chicago, IL 60611 USA

[6] Northwestern Univ, Dept Pharmacol, Feinberg Sch Med, Chicago, IL 60611 USA

[7] Northwestern Univ, Dept Anthropol, Weinberg Coll Arts & Sci, Evanston, IL 60208 USA

[8] Northwestern Univ, Inst Policy Res, Evanston, IL USA

来源：

ANNALS OF EPIDEMIOLOGY | 2022年 / 66卷

基金：

美国国家科学基金会;

关键词：

Covid-19; SARS-CoV-2; neighborhood; race; disparities; SARS-COV-2; RISK;

D O I：

10.1016/j.annepidem.2021.10.006

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

To date, COVID-19 case rates are disproportionately higher in Black and Latinx communities across the US, leading to more hospitalizations, and deaths in those communities. These differences in case rates are evident in comparisons of Chicago neighborhoods with differing race and/or ethnicities of their residents. Disparities could be due to neighborhoods with more adverse health outcomes associated with poverty and other social determinants of health experiencing higher prevalence of SARS-CoV-2 infection or due to greater morbidity and mortality resulting from equivalent SARS-CoV-2 infection prevalence. We surveyed five pairs of adjacent ZIP codes in Chicago with disparate COVID-19 case rates for highly specific and quantitative serologic evidence of any prior infection by SARS-CoV-2 to compare with their disparate COVID-19 case rates. Dried blood spot samples were self-collected at home by internet-recruited participants in summer 2020, shortly after Chicago's first wave of the COVID-19 pandemic. Pairs of neighboring ZIP codes with very different COVID-19 case rates had similar seropositivity rates for anti-SARS-CoV-2 receptor binding domain IgG antibodies. Overall, these findings of comparable exposure to SARS-CoV-2 across neighborhoods with very disparate COVID-19 case rates are consistent with social determinants of health, and the co-morbidities related to them, driving differences in COVID-19 rates across neighborhoods. (c) 2021 Elsevier Inc. All rights reserved.

引用

页码：44 / 51

页数：8