Update on Clinical Aspects of Chronic Obstructive Pulmonary Disease

被引:307
作者
Celli, Bartolome R. [1 ,2 ]
Wedzicha, Jadwiga A. [3 ]
机构
[1] Brigham & Womens Hosp, Pulm & Crit Care Div, 75 Francis St, Boston, MA 02115 USA
[2] Harvard Med Sch, Boston, MA 02115 USA
[3] Imperial Coll London, Natl Heart & Lung Inst, London, England
基金
英国医学研究理事会;
关键词
AIR-FLOW OBSTRUCTION; ACUTE EXACERBATIONS; NORMAL SPIROMETRY; RISK-FACTORS; COPD; MORTALITY; OUTCOMES; SMOKERS; FLUTICASONE; PREVENTION;
D O I
10.1056/NEJMra1900500
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A pair of review articles examines our current understanding of the biology, diagnosis, and treatment of chronic obstructive pulmonary disease. This article focuses on the clinical aspects of COPD.
引用
收藏
页码:1257 / 1266
页数:10
相关论文
共 75 条
  • [1] Abd-Allah F., 2018, LANCET, V392, P1736, DOI DOI 10.1016/S0140-6736(18)32203-7
  • [2] Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening
    Aberle, Denise R.
    Adams, Amanda M.
    Berg, Christine D.
    Black, William C.
    Clapp, Jonathan D.
    Fagerstrom, Richard M.
    Gareen, Ilana F.
    Gatsonis, Constantine
    Marcus, Pamela M.
    Sicks, JoRean D.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (05) : 395 - 409
  • [3] Avoiding confusion in COPD: from risk factors to phenotypes to measures of disease characterisation
    Agusti, A.
    Celli, B.
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2011, 38 (04) : 749 - 751
  • [4] Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease
    Agusti, Alvar
    Hogg, James C.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2019, 381 (13) : 1248 - 1256
  • [5] Inhaled corticosteroids in COPD: friend or foe?
    Agusti, Alvar
    Fabbri, Leonardo M.
    Singh, Dave
    Vestbo, Jorgen
    Celli, Bartolome
    Franssen, Frits M. E.
    Rabe, Klaus F.
    Papi, Alberto
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2018, 52 (06)
  • [6] Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype
    Agusti, Alvar
    Edwards, Lisa D.
    Rennard, Stephen I.
    MacNee, William
    Tal-Singer, Ruth
    Miller, Bruce E.
    Vestbo, Jorgen
    Lomas, David A.
    Calverley, Peter M. A.
    Wouters, Emiel
    Crim, Courtney
    Yates, Julie C.
    Silverman, Edwin K.
    Coxson, Harvey O.
    Bakke, Per
    Mayer, Ruth J.
    Celli, Bartolome
    [J]. PLOS ONE, 2012, 7 (05):
  • [7] A Randomized Trial of Long-Term Oxygen for COPD with Moderate Desaturation
    Albert, Richard K.
    Au, David H.
    Blackford, Amanda L.
    Casaburi, Richard
    Cooper, J. Allen, Jr.
    Criner, Gerard J.
    Diaz, Philip
    Fuhlbrigge, Anne L.
    Gay, Steven E.
    Kanner, Richard E.
    MacIntyre, Neil
    Martinez, Fernando J.
    Panos, Ralph J.
    Piantadosi, Steven
    Sciurba, Frank
    Shade, David
    Stibolt, Thomas
    Stoller, James K.
    Wise, Robert
    Yusen, Roger D.
    Tonascia, James
    Sternberg, Alice L.
    Bailey, William
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (17) : 1617 - 1627
  • [8] Azithromycin for Prevention of Exacerbations of COPD
    Albert, Richard K.
    Connett, John
    Bailey, William C.
    Casaburi, Richard
    Cooper, J. Allen D., Jr.
    Criner, Gerard J.
    Curtis, Jeffrey L.
    Dransfield, Mark T.
    Han, MeiLan K.
    Lazarus, Stephen C.
    Make, Barry
    Marchetti, Nathaniel
    Martinez, Fernando J.
    Madinger, Nancy E.
    McEvoy, Charlene
    Niewoehner, Dennis E.
    Porsasz, Janos
    Price, Connie S.
    Reilly, John
    Scanlon, Paul D.
    Sciurba, Frank C.
    Scharf, Steven M.
    Washko, George R.
    Woodruff, Prescott G.
    Anthonisen, Nicholas R.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (08) : 689 - 698
  • [9] The Presence of Chronic Mucus Hypersecretion across Adult Life in Relation to Chronic Obstructive Pulmonary Disease Development
    Allinson, James P.
    Hardy, Rebecca
    Donaldson, Gavin C.
    Shaheen, Seif O.
    Kuh, Diana
    Wedzicha, Jadwiga A.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193 (06) : 662 - 672
  • [10] Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease
    Anderson, Gary P.
    [J]. LANCET, 2008, 372 (9643) : 1107 - 1119