Microbial Transformation of Podocarpic Acid and Evaluation of Transformation Products for Antioxidant Activity

被引：6
作者：
Baraka, Hany Nashaat [1 ]
机构：
[1] Mansoura Univ, Fac Pharm, Dept Pharmacognosy, Mansoura 35516, Egypt
来源：
PLANTA MEDICA | 2010年 / 76卷 / 08期
关键词：
podocarpic acid; Mucor ramannianus ATCC 9628; Beauveria bassiana ATCC 7159; antioxidant; LIVER-X-RECEPTOR; AGONISTS; CHEMISTRY; DESIGN;
D O I：
10.1055/s-0029-1240738
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Podocarpic acid was metabolized by Mucor ramannianus ATCC 9628, and Beauveria bassiana ATCC 7159 to afford two new metabolites, 2 alpha-hydroxy podocarpic acid and 11-hydroxy podocarpic acid, along with the known metabolite 13-hydroxy podocarbic acid. The identity of these metabolites was verified using different spectral methods. The antioxidant activity of the metabolites was tested, and comparable results to those observed for ascorbic acid were obtained.
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页码：815 / 817
页数：3
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