The impact of cytomegalovirus infection ≥1 year after primary renal transplantation

被引：33
作者：
Browne, Barry J. [3 ]
Young, Jo-Anne [2 ]
Dunn, Ty B. [1 ]
Matas, Arthur J. [1 ]
机构：
[1] Univ Minnesota, Dept Surg, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Dept Med, Minneapolis, MN 55455 USA
[3] Balboa Nephrology Med Grp Inc, Transplant Serv, San Diego, CA USA
来源：
CLINICAL TRANSPLANTATION | 2010年 / 24卷 / 04期
关键词：
cytomegalovirus; renal transplant; infection; post transplant; late; LATE-ONSET; KIDNEY-TRANSPLANTATION; ANTIVIRAL PROPHYLAXIS; LIVER-TRANSPLANTATION; DISEASE; RECIPIENTS; REACTIVATION; GANCICLOVIR; PREVENTION; ACYCLOVIR;
D O I：
10.1111/j.1399-0012.2010.01208.x
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
We studied the impact of a first post-transplant cytomegalovirus (CMV) infection greater than one year after primary kidney transplantation. Risk factors for developing late CMV were acute rejection and donor-recipient CMV status. Of those developing late CMV, 35% were donor (D) positive, recipient (R) negative; however, 23% were D+R+, 22% D-R+, and 15% D-R-. Late CMV was associated with significantly decreased patient and graft survival.
引用
收藏
页码：572 / 577
页数：6
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