Cornual Ectopic Pregnancy: An Example of the Overdiagnosis of Molar Ectopic Pregnancy A Case Report

BACKGROUND: Molar ectopic pregnancies are rare. A literature search revealed that molar ectopic pregnancies are overdiagnosed. CASE: A 25-year-old, G5P3013, African American woman presented to a community hospital with sudden onset of sharp, stabbing, low abdominal pain and nausea and vomiting. Quantitative hCG was 6,644 mIU/mL and ultrasound demonstrated increased vascularity and a hypoechoic, partially tubular collection in the left adnexa concerning for ectopic pregnancy. Laparoscopy revealed a small amount of blood and a slight bulge in the left uterine cornu, which ruptured during blunt exploration. Laparotomy revealed the ruptured left uterine cornu with tissue protruding. A wedge resection of the cornu was performed. The pathologic findings from the cornual resection were consistent with a complete mole. Immunohistochemical staining was performed using p57 analysis 1.5 years later and was consistent with early ectopic pregnancy. CONCLUSION: p57 analysis is an important adjunct in the accurate diagnosis of ectopic hydatidiform molar pregnancy.