Exercise Has a Bone to Pick with Skeletal Muscle

被引:6
作者
Booth, Frank W. [1 ]
Ruegsegger, Gregory N. [1 ]
Olver, T. Dylan [1 ]
机构
[1] Univ Missouri, Dept Biomed Sci, Columbia, MO 65211 USA
关键词
METABOLISM;
D O I
10.1016/j.cmet.2016.05.016
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Exercise intolerance and poor exercise capacity are associated with aging, diabetes, cognitive impairment, and premature death. In this issue of Cell Metabolism, Mera et al. (2016) report that osteocalcin improves endurance exercise performance by enhancing myofiber fuel uptake and utilization, while osteocalcin supplementation reverses the age-induced decline in endurance exercise performance.
引用
收藏
页码:961 / 962
页数:2
相关论文
共 10 条
[1]  
Banting FG, 1922, CAN MED ASSOC J, V7, P141
[2]   Lack of Exercise Is a Major Cause of Chronic Diseases [J].
Booth, Frank W. ;
Roberts, Christian K. ;
Laye, Matthew J. .
COMPREHENSIVE PHYSIOLOGY, 2012, 2 (02) :1143-1211
[3]   Muscular exercise, lactic and, and the supply and utilisation of oxygen - Parts IV-VI [J].
Hill, AV ;
Long, CNH ;
Lupton, H .
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-CONTAINING PAPERS OF A BIOLOGICAL CHARACTER, 1924, 97 (681) :84-138
[4]   Regulation of carbohydrate and fat metabolism during and after exercise [J].
Holloszy, JO ;
Kohrt, WM .
ANNUAL REVIEW OF NUTRITION, 1996, 16 :121-138
[5]   Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication [J].
Karsenty, Gerard ;
Olson, Eric N. .
CELL, 2016, 164 (06) :1248-1256
[6]   Endocrine regulation of energy metabolism by the skeleton [J].
Lee, Na Kyung ;
Sowa, Hideaki ;
Hinoi, Eiichi ;
Ferron, Mathieu ;
Ahn, Jong Deok ;
Confavreux, Cyrille ;
Dacquin, Romain ;
Mee, Patrick J. ;
Mckee, Marc D. ;
Jung, Dae Young ;
Zhang, Zhiyou ;
Kim, Jason K. ;
Mauvais-Jarvis, Franck ;
Ducy, Patricia ;
Karsenty, Gerard .
CELL, 2007, 130 (03) :456-469
[7]   Osteoprotegerin is an effective countermeasure for spaceflight-induced bone loss in mice [J].
Lloyd, Shane A. ;
Morony, Sean E. ;
Ferguson, Virginia L. ;
Simske, Steven J. ;
Stodieck, Louis S. ;
Warmington, Kelly S. ;
Livingston, Eric W. ;
Lacey, David L. ;
Kostenuik, Paul J. ;
Bateman, Ted A. .
BONE, 2015, 81 :562-572
[8]   Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise [J].
Mera, Paula ;
Laue, Kathrin ;
Ferron, Mathieu ;
Confavreux, Cyril ;
Wei, Jianwen ;
Galan-Diez, Marta ;
Lacampagne, Alain ;
Mitchell, Sarah J. ;
Mattison, Julie A. ;
Chen, Yun ;
Bacchetta, Justine ;
Szulc, Pawel ;
Kitsis, Richard N. ;
de Cabo, Rafael ;
Friedman, Richard A. ;
Torsitano, Christopher ;
McGraw, Timothy E. ;
Puchowicz, Michelle ;
Kurland, Irwin ;
Karsenty, Gerard .
CELL METABOLISM, 2016, 23 (06) :1078-1092
[9]   Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis [J].
Oury, Franck ;
Ferron, Mathieu ;
Wang Huizhen ;
Confavreux, Cyrille ;
Xu, Lin ;
Lacombe, Julie ;
Srinivas, Prashanth ;
Chamouni, Alexandre ;
Lugani, Francesca ;
Lejeune, Herve ;
Kumar, T. Rajendra ;
Plotton, Ingrid ;
Karsenty, Gerard .
JOURNAL OF CLINICAL INVESTIGATION, 2013, 123 (06) :2421-2433
[10]   Four grams of glucose [J].
Wasserman, David H. .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2009, 296 (01) :E11-E21