Local drug delivery

被引：40
作者：
Haroun, RI [1 ]
Brem, H [1 ]
机构：
[1] Johns Hopkins Univ Hosp, Dept Neurol Surg, Baltimore, MD 21287 USA
来源：
CURRENT OPINION IN ONCOLOGY | 2000年 / 12卷 / 03期
关键词：
D O I：
10.1097/00001622-200005000-00001
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Intensive research efforts are now focused on the development of new strategies for more effective delivery of drugs to the central nervous system. These strategies include chemical modification of drugs, disruption of the blood-brain barrier, and utilization of alternative routes for drug delivery. This paper focuses on local drug delivery for the treatment of brain tumors, it reviews papers published in the past year on local chemotherapy and immunotherapy. Other aspects of local drug delivery are discussed, including convection-enhanced delivery and drug delivery via a controlled-release microchip. Curr Opin Oncol 2000, 12:187-193 (C) 2000 Lippincott Williams & Wilkins, Inc.
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收藏
页码：187 / 193
页数：7
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