Copper based facile, sensitive and low cost colorimetric assay for ampicillin sensing and quantification in nano delivery system

被引:15
作者
Kaur, Sarabjit [1 ,2 ]
Garg, Manish [3 ]
Mittal, Sherry [1 ,2 ]
Wangoo, Nishima [3 ]
Sharma, Rohit K. [1 ,2 ]
机构
[1] Panjab Univ, Dept Chem, Sect 14, Chandigarh 160014, India
[2] Panjab Univ, Ctr Adv Studies Chem, Sect 14, Chandigarh 160014, India
[3] Panjab Univ, Univ Inst Engn & Technol, Appl Sci Div, Sect 25, Chandigarh 160014, India
关键词
Ampicillin; Bicinchoninic acid; Copper based sensors; Chemosensors; Chitosan nanoparticles; Nano delivery system; BETA-LACTAM ANTIBIOTICS; LIQUID-CHROMATOGRAPHY; GOLD NANOPARTICLES; CONTROLLED-RELEASE; CHITOSAN; PROTEIN;
D O I
10.1016/j.snb.2017.03.143
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A novel colorimetric assay for quantification of ampicillin has been developed based on Cu-BCA complexation. The developed assay was optimized for determination of drug content in synthesized ampicillin loaded chitosan nanoparticles underlying its importance as a simple, sensitive and economical method for amplicillin quantification developed so far. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:234 / 239
页数:6
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