Give me a SIGN

被引：0

作者：

Jeffrey, Kate

机构：

来源：

NATURE MEDICINE | 2007年 / 13卷 / 07期

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In dendritic cells a unique signaling pathway gives human immunodeficiency virus (HIV) a distinct advantage for its replication and subsequent infection of CD-4-positive T cells. Dendritic cells capture foreign antigens with their diverse surface receptors and present the antigens to T cells. One receptor, DC-SIGN, is both an adhesion receptor that brings dendritic cells and T cells together and the recognition receptor for HIV, yet its downstream signaling pathway is unknown.

引用

页码：789 / 789

页数：1