Organocatalytic Direct β-Functionalization of Carbonyl Compounds

被引：0
作者：
Kawai, Hiroyuki
机构：
来源：
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN | 2014年 / 72卷 / 10期
关键词：
CARBOXYLIC ESTERS; C(SP(3))-H BONDS; ARYLATION; ACTIVATION; KETONES; PHOTOREDOX;
D O I：
10.5059/yukigoseikyokaishi.72.1154
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Functionalizations of carbonyl compounds are absolutely essential transformations in the field of organic synthesis. Carbonyl functional moieties readily react with nucleophiles (at ipso-carbon) and electrophiles (alpha-carbon substitution), however, the direct beta-functionalization of alpha,beta-saturated carbonyl compounds is rare, and poses a synthetic challenge. Two novel beta-activation methodologies appeared in 2013, enabled by organocatalysts.
引用
收藏
页码：1154 / 1155
页数：2
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