Synthesis of fluorine-containing oxazolonaphthalimide hydroperoxides as DNA photocleavers

被引：11

作者：

Yao, W

Qian, XH ^{[1
]}

机构：

[1] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116012, Peoples R China

[2] E China Univ Sci & Technol, Inst Pesticides & Pharmaceut, Shanghai 200237, Peoples R China

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2000年 / 106卷 / 01期

基金：

中国国家自然科学基金;

关键词：

fluorine-containing; oxazolonaphthalimide; hydroperoxides;

D O I：

10.1016/S0022-1139(00)00304-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Novel fluorine-containing hydroperoxides of oxazolonaphthalimide were designed and synthesized. The interactions of these compounds with DNA were studied. (C) 2000 Elsevier Science S.A. All rights reserved.

引用

页码：69 / 72

页数：4

共 10 条

[1] Photocleavage of nucleic acids [J].

Armitage, B .

CHEMICAL REVIEWS, 1998, 98 (03) :1171-1200

[2] Design, synthesis, and evaluation of N-aroyloxy-2-thiopyridones as DNA photocleaving reagents [J].

Blom, P ;

Xiang, AX ;

Kao, D ;

Theodorakis, EA .

BIOORGANIC & MEDICINAL CHEMISTRY, 1999, 7 (05) :727-736

[3] MOLECULAR STRUGGLE FOR TRANSCRIPTIONAL CONTROL [J].

HENDERSON, D ;

HURLEY, LH .

NATURE MEDICINE, 1995, 1 (06) :525-527

[4] DNA INTERCALATION AND PHOTOINDUCED CLEAVAGE BY 4-NITRO(N-HEXYLAMINE)1,8-NAPHTHALIMIDE [J].

MEHROTRA, J ;

MISRA, K ;

MISHRA, RK .

NUCLEOSIDES & NUCLEOTIDES, 1994, 13 (04) :963-978

[5] DESIGNED ENEDIYNES - A NEW CLASS OF DNA-CLEAVING MOLECULES WITH POTENT AND SELECTIVE ANTICANCER ACTIVITY [J].

NICOLAOU, KC ;

DAI, WM ;

TSAY, SC ;

ESTEVEZ, VA ;

WRASIDLO, W .

SCIENCE, 1992, 256 (5060) :1172-1178

[6] CHEMICAL NUCLEASES AS PROBES FOR STUDYING DNA-PROTEIN INTERACTIONS [J].

PAPAVASSILIOU, AG .

BIOCHEMICAL JOURNAL, 1995, 305 :345-357

[7]

PETERS AT, 1990, J SOC DYERS COLOUR, V106, P275

[8] PHTHALIMIDE HYDROPEROXIDES AS EFFICIENT PHOTOCHEMICAL HYDROXYL RADICAL GENERATORS - A NOVEL DNA-CLEAVING AGENT [J].

SAITO, I ;

TAKAYAMA, M ;

MATSUURA, T ;

MATSUGO, S ;

KAWANISHI, S .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (02) :883-884

[9] PHOTOCHEMISTRY OF HIGHLY ORGANIZED BIOMOLECULES - SEQUENCE-SELECTIVE PHOTOREACTION OF DNA [J].

SAITO, I .

PURE AND APPLIED CHEMISTRY, 1992, 64 (09) :1305-1310

[10] THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS [J].

SCATCHARD, G .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1949, 51 (04) :660-672

← 1 →