Effect of Hemodialysis on Peripapillary Choroidal Thickness Measured by Swept-Source Optical Coherence Tomography

被引:6
作者
Lee, Won June [1 ,3 ]
Hong, Rimkyung [1 ,4 ]
Kang, Min Ho [1 ,4 ]
Cho, Heeyoon [1 ,4 ]
Han, Sang-Woong [2 ]
Yi, Joo-Hark [2 ]
Shin, Yong Un [1 ,4 ]
Seong, Mincheol [1 ,4 ]
机构
[1] Hanyang Univ, Coll Med, Dept Ophthalmol, Guri, South Korea
[2] Hanyang Univ, Coll Med, Dept Internal Med, Div Nephrol, Guri, South Korea
[3] Hanyang Univ, Dept Ophthalmol, Seoul Hosp, Seoul, South Korea
[4] Hanyang Univ, Dept Ophthalmol, Guri Hosp, Guri, South Korea
基金
新加坡国家研究基金会;
关键词
swept-source optical coherence tomography; hemodialysis; peripapillary choroidal thickness; optic nerve head; end-stage kidney disease; OCULAR PERFUSION-PRESSURE; CHRONIC KIDNEY-DISEASE; NORMAL-TENSION GLAUCOMA; INTRAOCULAR-PRESSURE; BLOOD-PRESSURE; EYE DISEASES; RISK-FACTOR; RETINA; NERVE; FLUCTUATION;
D O I
10.1097/IJG.0000000000001762
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: The aim was to investigate the effects of hemodialysis (HD) on peripapillary choroidal thickness (PCT) by swept-source optical coherence tomography and on other ophthalmologic parameters in patients with end-stage kidney disease. Materials and Methods: This was a prospective observational study. The authors evaluated 29 patients who underwent HD for end-stage kidney disease. Detailed ophthalmologic examinations and swept-source optical coherence tomography were performed immediately before and after HD. PCT was measured using the modification tool in the built-in OCT image viewer program. Changes in PCT before and after HD were statistically analyzed. Results: The average PCT significantly decreased from 127.3 +/- 49.2 mu m before HD to 117.1 +/- 50.9 mu m after HD (P<0.001). A significant correlation was found between changes in PCT and macular choroidal thickness (rho=0.547, P=0.002). Changes in mean ocular perfusion pressure did not significantly correlate with changes in PCT (rho=-0.049, P=0.803). Conclusions: PCT significantly decreased after HD. HD could influence the optic nerve head and its surrounding structures.
引用
收藏
页码:459 / 464
页数:6
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