Long noncoding RNAs in regulating adipogenesis: new RNAs shed lights on obesity

被引：88

作者：

Wei, Shengjuan ^{[1
]}

Du, Min ^{[2
]}

Jiang, Zhihua ^{[2
]}

Hausman, Gary J. ^{[3
]}

Zhang, Lifan ^{[1
]}

Dodson, Michael V. ^{[2
]}

机构：

[1] Nanjing Agr Univ, Coll Anim Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China

[2] Washington State Univ, Dept Anim Sci, Pullman, WA 99164 USA

[3] Univ Georgia, Anim & Dairy Sci, Athens, GA 30602 USA

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 2016年 / 73卷 / 10期

基金：

中国国家自然科学基金;

关键词：

ncRNAs; Adipose tissue; Beige cells; SRA; HOTAIR; NEAT1; Blnc1; STEROID-RECEPTOR COACTIVATOR; ADIPOSE-TISSUE; WHITE ADIPOSE; HUMAN GENOME; H19; GENE; BROWN; EXPRESSION; LNCRNA; TRANSCRIPTION; REVEALS;

D O I：

10.1007/s00018-016-2169-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Long noncoding RNAs (lncRNAs) are an emerging class of regulators involved in a myriad of biological processes. Recent studies have revealed that many lncRNAs play pivotal roles in regulating adipocyte development. Due to the prevalence of obesity and the serious effects of adiposity on human health and society development, it is necessary to summarize functions and recent advances of lncRNAs in adipogenesis. In this review, we highlight functional lncRNAs contributed to the regulation of adipogenesis, discussing their potential use as therapeutic targets to combat human obesity.

引用

页码：2079 / 2087

页数：9

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