Reaction-based AIE-active Fluorescent Probes for Selective Detection and Imaging

被引：41

作者：

Gao, Xiaoying ^{[1
]}

Sun, Jing Zhi ^{[1
]}

Tang, Ben Zhong ^{[1
,2
]}

机构：

[1] Zhejiang Univ, Dept Polymer Sci & Engn, MOE Key Lab Macromol Synth & Functionalizat, Hangzhou 310027, Zhejiang, Peoples R China

[2] Hong Kong Univ Sci & Technol, Chinese Natl Engn Res Ctr Tissue Restorat & Recon, State Key Lab Mol Neurosci,Div Life Sci,Hong Kong, Inst Mol Funct Mat,Div Biomed Engn,Dept Chem, Kowloon, Hong Kong, Peoples R China

来源：

ISRAEL JOURNAL OF CHEMISTRY | 2018年 / 58卷 / 08期

基金：

美国国家科学基金会;

关键词：

reaction-based probe; aggregation-induced emission; fluorescence; detection; imaging; AGGREGATION-INDUCED EMISSION; LIGHT-UP PROBE; TURN-ON DETECTION; MAST-CELLS; IN-VIVO; LIQUID-CHROMATOGRAPHY; RATIOMETRIC DETECTION; ALKALINE-PHOSPHATASE; HYDROGEN-SULFIDE; CHEMISTRY;

D O I：

10.1002/ijch.201800035

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fluorescent probes have been widely investigated for their features of rapid response, easy operation and high sensitivity. Among them, reaction-based fluorescent probes, for their unique reaction-based nature, guarantee them with excellent selectivity, effectively avoiding the possible interference from other chemical and biological species in physiological environment. Conventional reaction-based fluorescent probes are aggregation-caused quenching (ACQ) fluorophores. The application of these kinds of probes are limited for their poor photostability and narrow Stokes shifts. Compared with ACQ fluorophores, aggregation-induced emission (AIE) fluorophores become emissive in aggregation states with higher signal-to-noise ratio, better photostability and larger Stokes shifts. In this review, we summarize the latest developed reaction-based AIE-active probes, including the design principle and application in various sensing systems and give an outlook for the future development of this kind of promising fluorescent probes.

引用

页码：845 / 859

页数：15

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