Clinical outcomes of patients with mitral prosthetic valve obstructive thrombosis treated with streptokinase or tenecteplase

被引：1
作者：
Kiran, G. Ravi [1 ]
Chandrasekhar, P. [1 ]
Ali, S. Mohammad [2 ]
机构：
[1] Kurnool Med Coll & Hosp, Dept Cardiol, Kurnool, Andhra Pradesh, India
[2] KIMS Hosp, Kurnool, Andhra Pradesh, India
来源：
INDIAN HEART JOURNAL | 2021年 / 73卷 / 03期
关键词：
Prosthetic valve thrombosis; Stuck valve; Prosthetic valve; Thrombolytic therapy; Tenecteplase; Streptokinase; Systematic review; THROMBOLYTIC THERAPY; FIBRINOLYTIC THERAPY; ECHOCARDIOGRAPHY; SURGERY;
D O I：
10.1016/j.ihj.2021.02.005
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Agent of choice for thrombolytic therapy (TT) in prosthetic valve thrombosis (PVT) is unknown. 84 mitral obstructive-PVT episodes treated with TT (43: Tenecteplase; 41: Streptokinase) were included in this prospective study. The incidence of primary end-point (CCS: complete clinical success, defined as complete or partial hemodynamic success with no complications or surgery) was 84.5% with recurrent PVT as a sole predictor. Bleeding and embolic manifestations were noted in 8.3% and 4.7% of episodes respectively. Tenecteplase use was associated with lower complication rate and a mitral EOA of <0.74 cm(2) at presentation predicts the need for extended thrombolysis (accuracy, 78.6%). (C) 2021 Cardiological Society of India. Published by Elsevier B.V.
引用
收藏
页码：365 / 368
页数：4
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