Cyclosporin A-related cerebral venous sinus thrombosis A case report

被引:4
作者
Gao, Fengjuan [1 ,2 ]
Zhang, Jun [1 ,2 ]
Wang, Fang [1 ,2 ]
Xin, Xiaoyan [2 ,3 ]
Sha, Dujuan [1 ,2 ]
机构
[1] Nanjing Univ, Sch Med, Nanjing Drum Tower Hosp, Dept Emergency, 321 Zhongshan Rd, Nanjing 210008, Jiangsu, Peoples R China
[2] Nanjing Univ, State Key Lab Pharmaceut Biotechnol, Nanjing, Jiangsu, Peoples R China
[3] Nanjing Univ, Sch Med, Dept Radiol, Nanjing Drum Tower Hosp, Nanjing, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
cerebral venous sinus thrombosis; cyclosporin A; headache; SUPERIOR SAGITTAL SINUS; TAMOXIFEN TREATMENT; BREAST-CANCER; RISK-FACTOR; PATIENT; ANEMIA; OLD;
D O I
10.1097/MD.0000000000011642
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Rationale: Cerebral venous sinus thrombosis (CVST) is a complex life-threatening condition, and its etiology is not well understood. Although oral cyclosporin A is not a common cause of the symptoms related to CVST, there is limited information available. Patient concerns: In this study, we report a rare case of CVST in a 44-year-old woman with aplastic anemia, who was given cyclosporin A orally for a period of 18 months. She had experienced a headache for 20 days. Diagnoses: The patient was diagnosed with CVST by computed tomography venography. Interventions: Low molecular heparin (enoxaparin, 4000 AXaIU, subcutaneous injection, once every 12 hours) was administered for anticoagulation. Outcomes: The patient developed no recurrence of thrombosis during the 13-month follow-up period. Lessons: Clinicians should be aware of the possibility of CVST when patients are treated with cyclosporin A and have symptoms such as headaches.
引用
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页数:4
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