Gonadal histology and characteristic histopathology associated with endocrine disruption in the adult fathead minnow (Pimephales promelas)

被引：98
作者：
Leino, RL [1 ]
Jensen, KM
Ankley, GT
机构：
[1] Univ Minnesota, Sch Med, Dept Anat & Cell Biol, Duluth, MN 55812 USA
[2] US EPA, Mid Continent Ecol Div, Duluth, MN 55804 USA
来源：
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY | 2005年 / 19卷 / 01期
关键词：
fish; ovary; testis; histology; endocrine disruptors;
D O I：
10.1016/j.etap.2004.05.010
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Examination of gonadal histopathology has been beneficial in understanding and assessing die effects of potential endocrine disrupting. chemicals in fish and other organisms. The present study describes the normal gonadal histology of the fathead minnow (Pimephales promelas), a widely used test organism, reviews typical effects of endocrine disrupting chemicals with different modes/mechanisms of action on the histological structure of the ovaries and testes. and recommends methods for optimizing histopathological results. (C) 2004 Elsevier B.V. All rights reserved.
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页码：85 / 98
页数：14
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