Reversible Cerebral Vasoconstriction Syndromes and Primary Angiitis of the Central Nervous System: Clinical, Imaging, and Angiographic Comparison
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作者:
Singhal, Aneesh B.
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Massachusetts Gen Hosp, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USAMassachusetts Gen Hosp, Boston, MA 02114 USA
Singhal, Aneesh B.
[1
,2
]
Topcuoglu, Mehmet A.
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机构:
Massachusetts Gen Hosp, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USA
Hacettepe Univ Hosp, Dept Neurol, Ankara, TurkeyMassachusetts Gen Hosp, Boston, MA 02114 USA
Topcuoglu, Mehmet A.
[1
,2
,3
]
Fok, Joshua W.
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机构:
Yan Chai Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R ChinaMassachusetts Gen Hosp, Boston, MA 02114 USA
Fok, Joshua W.
[4
]
Kursun, Oguzhan
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机构:
Ankara Numune Training & Res Hosp, Neurol Clin, Ankara, TurkeyMassachusetts Gen Hosp, Boston, MA 02114 USA
Kursun, Oguzhan
[5
]
Nogueira, Raul G.
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Grady Mem Hosp, Atlanta, GA USA
Emory Univ, Sch Med, Atlanta, GA USAMassachusetts Gen Hosp, Boston, MA 02114 USA
Nogueira, Raul G.
[6
,7
]
Frosch, Matthew P.
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Massachusetts Gen Hosp, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USAMassachusetts Gen Hosp, Boston, MA 02114 USA
Frosch, Matthew P.
[1
,2
]
Caviness, Verne S., Jr.
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Massachusetts Gen Hosp, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USAMassachusetts Gen Hosp, Boston, MA 02114 USA
Caviness, Verne S., Jr.
[1
,2
]
机构:
[1] Massachusetts Gen Hosp, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
[3] Hacettepe Univ Hosp, Dept Neurol, Ankara, Turkey
[4] Yan Chai Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
[5] Ankara Numune Training & Res Hosp, Neurol Clin, Ankara, Turkey
Reversible cerebral vasoconstriction syndromes (RCVS) and primary angiitis of the central nervous system (PACNS) are invariably considered in the differential diagnosis of new cerebral arteriopathies. However, prompt and accurate diagnosis remains challenging. Here we compared the features of 159 RCVS to 47 PACNS patients and developed criteria for prompt bedside diagnosis. Recurrent thunderclap headache (TCH), and single TCH combined with either normal neuroimaging, border zone infarcts, or vasogenic edema, have 100% positive predictive value for diagnosing RCVS or RCVS-spectrum disorders. In patients without TCH and positive angiography, neuroimaging can discriminate RCVS (no lesion) from PACNS (deep/brainstem infarcts).
机构:
John H Stroger Hosp Cook Cty, Dept Med, 1950 W Polk, Chicago, IL 60612 USAJohn H Stroger Hosp Cook Cty, Dept Med, 1950 W Polk, Chicago, IL 60612 USA
Lopez-Arevalo, Hugo
Noboa, Maria Emilia Romero
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机构:
John H Stroger Hosp Cook Cty, Dept Med, 1950 W Polk, Chicago, IL 60612 USAJohn H Stroger Hosp Cook Cty, Dept Med, 1950 W Polk, Chicago, IL 60612 USA
Noboa, Maria Emilia Romero
Joseph, Dijo
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机构:
Rush Univ, Div Rheumatol, Med Ctr, 1611 W Harrison St,Suite 510, Chicago, IL 60612 USAJohn H Stroger Hosp Cook Cty, Dept Med, 1950 W Polk, Chicago, IL 60612 USA
Joseph, Dijo
Edigin, Ehizogie
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机构:
Loma Linda Univ Hlth, Dept Rheumatol, Loma Linda, CA USAJohn H Stroger Hosp Cook Cty, Dept Med, 1950 W Polk, Chicago, IL 60612 USA
Edigin, Ehizogie
Arora, Shilpa
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机构:
John H Stroger Hosp Cook Cty, 1950 W Polk,5th Floor, Chicago, IL 60612 USAJohn H Stroger Hosp Cook Cty, Dept Med, 1950 W Polk, Chicago, IL 60612 USA
Arora, Shilpa
Manadan, Augustine
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机构:
Rush Univ, Div Rheumatol, Med Ctr, 1611 W Harrison St,Suite 510, Chicago, IL 60612 USAJohn H Stroger Hosp Cook Cty, Dept Med, 1950 W Polk, Chicago, IL 60612 USA