Khat-induced liver injuries: A report of two cases

被引：3

作者：

Alhaddad, Omkolsoum M. ^{[1
]}

Elsabaawy, Maha M. ^{[1
]}

Rewisha, Eman A. ^{[1
]}

Salman, Tary A. ^{[1
]}

Kohla, Mohamed A. S. ^{[1
]}

Ehsan, Nermine A. ^{[2
]}

Waked, Imam A. ^{[1
]}

机构：

[1] Menoufiya Univ, Natl Liver Inst, Dept Hepatol, Shibin Al Kawm 234511, Egypt

[2] Menoufiya Univ, Natl Liver Inst, Dept Pathol, Shibin Al Kawm 234511, Egypt

来源：

ARAB JOURNAL OF GASTROENTEROLOGY | 2016年 / 17卷 / 01期

关键词：

Khat; Induced; Liver; Injury; CATHINONE;

D O I：

10.1016/j.ajg.2016.02.002

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Khat is consumed for recreational purposes in many countries, including Yemen, where > 50% of adults chew khat leaves regularly. A wide spectrum of khat-induced liver injuries has been reported in the literature. Herein, we report two patients with khat-induced liver injury. Both patients clinically presented with acute hepatitis, one of whom showed radiological evidence of hepatic outflow obstruction. Based on the histological tests, both patients had acute hepatitis, which indicated drug-induced liver injury (DILI) on a background of chronic hepatitis and portal fibrosis; of the two, one presented with symptoms of immune-mediated liver injury. (C) 2016 Arab Journal of Gastroenterology. Published by Elsevier B.V. All rights reserved.

引用

页码：45 / 48

页数：4

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