Selenium/tellurium containing polymer materials in nanobiotechnology

被引：175

作者：

Cao, Wei ^{[1
]}

Wang, Lu ^{[1
]}

Xu, Huaping ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China

来源：

NANO TODAY | 2015年 / 10卷 / 06期

基金：

中国国家自然科学基金; 美国国家科学基金会;

关键词：

Selenium-containing polymer; Tellurium-containing polymer; Self-assembly; Nano-materials; Controlled delivery; Stimuli response; SYNTHETIC ORGANOSELENIUM COMPOUNDS; GLUTATHIONE-PEROXIDASE ACTIVITY; BLOCK-COPOLYMER MICELLES; BY-LAYER FILMS; DRUG-DELIVERY; NITRIC-OXIDE; GENE DELIVERY; HYPERBRANCHED POLYMERS; RADICAL POLYMERIZATION; SINGLE DISELENIDE;

D O I：

10.1016/j.nantod.2015.11.004

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Selenium/tellurium containing polymers have been attracting growing interest due to their unique properties and potential applications as bio-nanomaterials. The introduction of selenium or tellurium chemistry into block copolymers endows self-assembled nanomaterials with novel stimuli responsiveness and enhanced sensitivity. This review article provides an overview on recent advances of selenium/tellurium containing polymers. We summarize the redox response and reversible self-assembly behaviors, gamma-ray responsive systems for combined chemo- and radio-therapies, and coordination-responsive systems for controlled delivery are highlighted. The review then reveals how selenium-containing polymers can modulate reactive oxygen species and work as gene delivery vehicles or self-delivery therapeutics. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：717 / 736

页数：20

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