Effectiveness of the Comirnaty (BNT162b2, BioNTech/Pfizer) vaccine in preventing SARS-CoV-2 infection among healthcare workers, Treviso province, Veneto region, Italy, 27 December 2020 to 24 March 2021

被引：75
作者：
Fabiani, Massimo [1 ]
Ramigni, Mauro [2 ]
Gobbetto, Valentina [2 ]
Mateo-Urdiales, Alberto [1 ,3 ]
Pezzotti, Patrizio [1 ]
Piovesan, Cinzia [2 ]
机构：
[1] Ist Super Sanita, Dept Infect Dis, Rome, Italy
[2] Local Hlth Unit ULSS 2 Marca Trevigiana, Treviso, Italy
[3] European Ctr Dis Prevent & Control ECDC, European Programme Intervent Epidemiol Training E, Stockholm, Sweden
来源：
EUROSURVEILLANCE | 2021年 / 26卷 / 17期
关键词：
D O I：
10.2807/1560-7917.ES.2021.26.17.2100420
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Data on effectiveness of the BioNTech/Pfizer COVID-19 vaccine in real-world settings are limited. In a study of 6,423 healthcare workers in Treviso Province, Italy, we estimated that, within the time intervals of 14-21 days from the first and at least 7 days from the second dose, vaccine effectiveness in preventing SARS-CoV-2 infec-tion was 84% (95% confidence interval (CI): 40-96) and 95% (95% CI: 62-99), respectively. These results could support the ongoing vaccination campaigns by providing evidence for targeted communication.
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页码：1 / 7
页数：7
相关论文
共 11 条
  • [1] Early rate reductions of SARS-CoV-2 infection and COVID-19 in BNT162b2 vaccine recipients
    Amit, Sharon
    Regev-Yochay, Gili
    Afek, Arnon
    Kreiss, Yitshak
    Leshem, Eyal
    [J]. LANCET, 2021, 397 (10277) : 875 - 877
  • [2] Impact of a Nationwide Lockdown on SARS-CoV-2 Transmissibility, Italy
    Guzzetta, Giorgio
    Riccardo, Flavia
    Marziano, Valentina
    Poletti, Piero
    Trentini, Filippo
    Bella, Antonino
    Andrianou, Xanthi
    Del Manso, Martina
    Fabiani, Massimo
    Bellino, Stefania
    Boros, Stefano
    Urdiales, Alberto Mateo
    Vescio, Maria Fenicia
    Piccioli, Andrea
    Brusaferro, Silvio
    Rezza, Giovanni
    Pezzotti, Patrizio
    Ajelli, Marco
    Merler, Stefano
    [J]. EMERGING INFECTIOUS DISEASES, 2021, 27 (01) : 267 - 270
  • [3] Hall VJ, 2021, LANCET
  • [4] Istituto Superiore di Sanita, 2022, TASK FORC COVID 19 D
  • [5] Italian Medicines Agency (AIFA), BIONTECH PFIZ VACC A
  • [6] Italian Ministry of Health, COV 19 NEW MIN DECR
  • [7] Lee K, 2009, GLOB INST, P1
  • [8] Manica M., 2021, IMPACT TIERED RESTRI, DOI [10.1101/2021.01.10.21249532, DOI 10.1101/2021.01.10.21249532]
  • [9] Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
    Polack, Fernando P.
    Thomas, Stephen J.
    Kitchin, Nicholas
    Absalon, Judith
    Gurtman, Alejandra
    Lockhart, Stephen
    Perez, John L.
    Perez Marc, Gonzalo
    Moreira, Edson D.
    Zerbini, Cristiano
    Bailey, Ruth
    Swanson, Kena A.
    Roychoudhury, Satrajit
    Koury, Kenneth
    Li, Ping
    Kalina, Warren V.
    Cooper, David
    Frenck, Robert W., Jr.
    Hammitt, Laura L.
    Tureci, Ozlem
    Nell, Haylene
    Schaefer, Axel
    Unal, Serhat
    Tresnan, Dina B.
    Mather, Susan
    Dormitzer, Philip R.
    Sahin, Ugur
    Jansen, Kathrin U.
    Gruber, William C.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (27) : 2603 - 2615
  • [10] Public Health England (PHE), ANN A REP JCVI EST E
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