The Effects of Continuation-Maintenance Electroconvulsive Therapy on Reducing Hospital Re-Admissions in Patients with Treatment-Resistant Schizophrenia

被引：7
作者：
Choi, Kyung Mook [1 ]
Choi, Soo-Hee [1 ,2 ,3 ]
Hong, Jung Kyung [1 ]
Lee, Mi Hyun [1 ]
Jung, Joon Hyung [1 ]
Oh, Sang Hoon [1 ]
Jung, Dong Chung [1 ]
Kim, Sung Nyun [1 ]
机构：
[1] Seoul Natl Univ Hosp, Dept Neuropsychiat, 101 Daehak Ro, Seoul 03080, South Korea
[2] Seoul Natl Univ, Coll Med, Dept Psychiat, Seoul, South Korea
[3] Seoul Natl Univ, Coll Med, Inst Human Behav Sci, Seoul, South Korea
来源：
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE | 2018年 / 16卷 / 03期
基金：
新加坡国家研究基金会;
关键词：
Electroconvulsive therapy; Schizophrenia; Treatment-resistance; Recurrence; Hospitalization; REFRACTORY SCHIZOPHRENIA; CLOZAPINE; AUGMENTATION;
D O I：
10.9758/cpn.2018.16.3.339
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Objective: Continuation-maintenance electroconvulsive therapy (C/M-ECT) is used to prevent relapse or recurrence in patients with severe mental illnesses. We aimed to investigate the effect of C/M-ECT on reducing hospital re-admissions in patients with treatment-resistant schizophrenia. Methods: We applied a mirror-image design by retrospectively examining re-hospitalization rates of 18 patients with schizophrenia spectrum disorders. We compared the numbers of psychiatric admissions during the actual period over which C/M-ECT was administered with the same period prior to the beginning of C/M-ECT. Results: The number of psychiatric admissions was reduced significantly during C/M-ECT (0.33 +/- 0.77) compared with that of the same period prior to C/M-ECT (2.67 +/- 1.33) (Wilcoxon signed rank Z= - 3.663; p<0.001). Conclusion: This finding shows that C/M-ECT augmentation could successfully reduce the re-hospitalization rates in patients with treatment-resistant schizophrenia.
引用
收藏
页码：339 / 342
页数：4
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